口香糖消费对人体测量特征和心脏疾病的影响：随机对照试验的系统评价和荟萃分析。
The effect of gum consumption on anthropometric characteristics and cardiac disorders: A systematic review and meta-analysis of randomized controlled trials.
机构信息
Department of Cardiology, Ganzhou People's Hospital, Meiguan Avenue, Ganzhou City, Jiangxi Province 341000, China.
School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
Complement Ther Med. 2020 Nov;54:102578. doi: 10.1016/j.ctim.2020.102578. Epub 2020 Sep 22.
OBJECTIVE
No systematic review and (or) meta-analysis has been conducted so far to study the effect of gum consumption on anthropometric indices and blood pressure. Thus, our objective was to conduct a systematic review and meta-analysis of the randomized controlled trials investigating the effect of gum consumption on anthropometric indices and cardiac disorders.
METHODS
The literature search was implemented in the Scopus, Web of Science, PubMed/Medline and Google Scholar databases to discover trials that investigated the impact of gum on obesity indices and cardiac disorders up to April 2019. In order to calculate effect sizes, the random-effects model (using the DerSimonian-Laird method) was applied.
RESULTS
Finally, 21 articles were included in this meta-analysis. Combined results indicated that body weight (WMD: -0.60 kg, 95 % CI: -1.13, -0.07, P = 0.026, I = 89 %), and WC (WMD: -1.36 cm, 95 % CI: -2.50, -0.22, P = 0.019, I = 96 %) changed significantly following gum consumption. Subgroup analyses showed that a gum dosage ≤15 g/day (WMD: -1.23 kg/m2, 95 % CI: -2.03 to -0.43, I2 = 99 %) significantly decreased BMI. Moreover, gum consumption had significant effects on cardiac disorders.
CONCLUSION
In conclusion, gum supplementation may be an adjuvant for controlling obesity and can possess potential benefits in the management of cardiac disorders.
目的
目前尚未进行系统评价和/或荟萃分析来研究咀嚼口香糖对人体测量学指标和血压的影响。因此，我们的目的是对评估咀嚼口香糖对人体测量学指标和心脏疾病影响的随机对照试验进行系统评价和荟萃分析。
方法
在 Scopus、Web of Science、PubMed/Medline 和 Google Scholar 数据库中进行文献检索，以发现截至 2019 年 4 月评估口香糖对肥胖指数和心脏疾病影响的试验。为了计算效应大小，应用了随机效应模型（使用 DerSimonian-Laird 方法）。
结果
最终，本荟萃分析纳入了 21 篇文章。综合结果表明，体重（WMD：-0.60kg，95%CI：-1.13，-0.07，P=0.026，I²=89%）和 WC（WMD：-1.36cm，95%CI：-2.50，-0.22，P=0.019，I²=96%）在咀嚼口香糖后显著变化。亚组分析表明，咀嚼口香糖剂量≤15g/天（WMD：-1.23kg/m²，95%CI：-2.03 至-0.43，I²=99%）可显著降低 BMI。此外，咀嚼口香糖对心脏疾病有显著影响。
结论
总之，咀嚼口香糖补充剂可能是控制肥胖的辅助手段，并可能在心脏疾病管理中具有潜在益处。
Zotero 插件