咪达唑仑：一种用于牙科的多功能药物综述。
Midazolam: review of a versatile agent for use in dentistry.
作者信息
Giovannitti J A
出版信息
Anesth Prog. 1987 Sep-Oct;34(5):164-70.
Abstract
Midazolam is a relatively new benzodiazepine that is widely used in both medicine and dentistry. Its multiplicity of uses makes it unique among the benzodiazepines, and its water solubility and lack of active metabolites give it distinct advantages over diazepam. This paper reviews the clinical pharmacology of midazolam, provides comparison with diazepam and presents current information regarding its indications, limitations, advantages, disadvantages, methods of administration and precautions for use.
摘要
咪达唑仑是一种相对较新的苯二氮䓬类药物，广泛应用于医学和牙科领域。其多种用途使其在苯二氮䓬类药物中独具特色，且其水溶性和无活性代谢产物使其比地西泮具有明显优势。本文综述了咪达唑仑的临床药理学，与地西泮进行了比较，并介绍了其适应证、局限性、优点、缺点、给药方法及使用注意事项的当前信息。
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Midazolam: review of a versatile agent for use in dentistry.咪达唑仑：一种用于牙科的多功能药物综述。
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引用本文的文献
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Midazolam and its effect on vital signs and behavior in children under conscious sedation in dentistry.咪达唑仑及其在牙科镇静下儿童生命体征和行为的影响。
Physiol Res. 2020 Sep 30;69(Suppl 2):S305-S314. doi: 10.33549/physiolres.934511.
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A comparison of transcutaneous PO2 in patients sedated with diazepam-fentanyl or midazolam-fentanyl.使用地西泮-芬太尼或咪达唑仑-芬太尼镇静的患者经皮氧分压的比较。
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本文引用的文献
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Respiratory depression by midazolam and diazepam.咪达唑仑和地西泮所致的呼吸抑制
Anesthesiology. 1980 Dec;53(6):494-7. doi: 10.1097/00000542-198012000-00010.
2
Inhibition of GABA metabolism in rat brain synaptosomes by midazolam (RO-21-3981).咪达唑仑（RO-21-3981）对大鼠脑突触体中γ-氨基丁酸代谢的抑制作用。
Anesthesiology. 1981 Jul;55(1):41-5. doi: 10.1097/00000542-198107000-00009.
3
Benzodiazepines protect mice from local anesthetic convulsions and deaths.苯二氮䓬类药物可保护小鼠免受局部麻醉药引起的惊厥和死亡。
Anesth Analg. 1981 Jun;60(6):385-9.
4
Physostigmine reversal of midazolam-induced sedation.毒扁豆碱对咪达唑仑所致镇静作用的逆转
Anesthesiology. 1982 Aug;57(2):125-7. doi: 10.1097/00000542-198208000-00011.
5
Midazolam in paediatric anaesthesia.咪达唑仑在小儿麻醉中的应用
Anaesth Intensive Care. 1982 Feb;10(1):36-9. doi: 10.1177/0310057X8201000108.
6
Midazolam for induction of anaesthesia in outpatients: a comparison with thiopentone.咪达唑仑用于门诊患者麻醉诱导：与硫喷妥钠的比较。
Acta Anaesthesiol Scand. 1981 Dec;25(6):492-6. doi: 10.1111/j.1399-6576.1981.tb01693.x.
7
Cardiovascular effects of midazolam and thiopentone for induction of anaesthesia in ill surgical patients.咪达唑仑和硫喷妥钠用于外科重症患者麻醉诱导的心血管效应
Can Anaesth Soc J. 1983 Jan;30(1):19-23. doi: 10.1007/BF03007711.
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Specific benzodiazepine antagonist RO15-1788 and thirst-induced drinking in the rat.特定苯二氮䓬拮抗剂RO15 - 1788与大鼠口渴诱导饮水
Neuropharmacology. 1982 May;21(5):483-6. doi: 10.1016/0028-3908(82)90036-3.
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Premedication with intramuscular midazolam: a prospective randomized double-blind controlled study.肌肉注射咪达唑仑进行术前用药：一项前瞻性随机双盲对照研究。
Anesth Analg. 1982 Nov;61(11):933-7.
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A comparison of midazolam and diazepam for intravenous sedation in dentistry.
Anaesthesia. 1984 Jun;39(6):589-93. doi: 10.1111/j.1365-2044.1984.tb07370.x.
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