Surti Suleman, Karp Joel S
Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Phys Med. 2020 Dec;80:251-258. doi: 10.1016/j.ejmp.2020.10.031. Epub 2020 Nov 16.
This paper provides an update on time-of-flight (TOF) PET with a focus on latest hardware developments leading to current commercial PET/CT instruments. We describe advances in scintillator development, new photosensors and associated electronics readout, and detector designs for utilization in complete systems. Next, we introduce the latest commercial PET/CT scanners based on the aforementioned technologies, and discuss the detector design choices made that are relevant to differences in the system performance. Finally, we end with a discussion of the latest performance benchmarks for improved timing in PET detectors, challenges in scaling this performance to a complete system, and the outlook towards achieving a sub-50 ps coincidence timing resolution (CTR) in a PET detector.
本文提供了关于飞行时间(TOF)正电子发射断层扫描(PET)的最新进展,重点关注导致当前商用PET/CT仪器的最新硬件发展。我们描述了闪烁体开发、新型光电传感器及相关电子读出技术的进展,以及用于完整系统的探测器设计。接下来,我们介绍基于上述技术的最新商用PET/CT扫描仪,并讨论与系统性能差异相关的探测器设计选择。最后,我们讨论了PET探测器中用于改善时间分辨率的最新性能基准、将这种性能扩展到完整系统所面临的挑战,以及在PET探测器中实现低于50皮秒符合时间分辨率(CTR)的前景。