Pan Yueying, Xia Liming, Wang Yujin, Guan Hanxiong
Radiology Department, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
J Int Med Res. 2020 Nov;48(11):300060520972913. doi: 10.1177/0300060520972913.
To observe the evolution of chest high-resolution computed tomography (HRCT) manifestations in 105 patients with coronavirus disease 2019 (COVID-19).
One hundred five patients with confirmed COVID-19 were enrolled from 11 January to 9 February 2020. Sequential chest HRCT examinations were performed. Five stages were identified from the onset of initial symptoms: 0-3, 4-7, 8-14, 15-21, and >21 days (Stages A-E, respectively). A semi-quantitative CT scoring system was used to estimate the sum of lung abnormalities in each stage.
In total, 393 CT scans were collected. The patients underwent 3.8 ± 1.5 CT examinations. Multiple lobes were involved in most cases. The proportion of consolidation and the total CT score gradually increased from Stage A to C and gradually decreased from Stage C to E. The total CT score of lung involvement was significantly higher in Stage C than in Stages B and D. The CT score of the lower lobe was significantly higher than the corresponding upper and middle lobes in Stages A to D.
Most patients with COVID-19 had a disease course of >14 days, and the lung lesions in most patients improved after 14 days since initial symptom onset.
观察105例新型冠状病毒肺炎（COVID-19）患者胸部高分辨率计算机断层扫描（HRCT）表现的演变。
选取2020年1月11日至2月9日确诊的105例COVID-19患者，进行胸部HRCT连续检查。从初始症状出现开始确定五个阶段：0 - 3天、4 - 7天、8 - 14天、15 - 21天和>21天（分别为A - E期）。采用半定量CT评分系统评估各阶段肺部异常的总和。
共收集393份CT扫描图像。患者接受了3.8±1.5次CT检查。大多数病例累及多个肺叶。实变比例和总CT评分从A期到C期逐渐增加，从C期到E期逐渐降低。C期肺受累的总CT评分显著高于B期和D期。在A至D期，下叶的CT评分显著高于相应的上叶和中叶。
大多数COVID-19患者病程>14天，大多数患者肺部病变在初始症状出现14天后有所改善。
