The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Nat Commun. 2020 Nov 19;11(1):5900. doi: 10.1038/s41467-020-19653-5.
Over the past 15 years, genome-wide association studies (GWASs) have generated a wealth of new information. Larger samples sizes, refined phenotypes and higher-resolution genome-screens will continue to drive gene discovery in years ahead. Meanwhile, GWAS loci are increasingly translated into new biology and opportunities for clinical care.
在过去的 15 年中，全基因组关联研究（GWAS）已经产生了大量的新信息。更大的样本量、更精细的表型和更高分辨率的基因组筛选将在未来几年继续推动基因发现。与此同时，GWAS 研究也越来越多地转化为新的生物学研究，并为临床治疗提供了新的机会。
