Gamboa Elizabeth, Duran Melanie, Gathe Joseph C, Surani Salim, Varon Joseph
Medicine, Universidad Xochicalco, Ensenada, MEX.
Internal Medicine, United Memorial Medical Center, Houston, USA.
Cureus. 2020 Oct 17;12(10):e11007. doi: 10.7759/cureus.11007.
The newly discovered severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has impacted the world dramatically, forcing the medical community to quickly and effectively find ways to manage coronavirus disease 2019 (COVID-19). The COVID-19 pandemic has shown many similarities to the human immunodeficiency virus pandemic in 1981, from the fear of treating patients for a virus we have little knowledge of, to analyzing how the levels of CD4+ are affected in both diseases. Declining numbers of CD4+ levels are classically seen with HIV patients, however, given the immune response of our bodies, these levels have also been seen to decrease during an active COVID-19 infection. Besides, there is speculation that people living with HIV are at a higher risk for mortality if infected with SARS-CoV-2. Therefore, the interaction of these two viruses can create a syndemic culture, and thus, the need to monitor and treat patients with human immunodeficiency virus and COVID-19 cautiously.
新发现的严重急性呼吸综合征冠状病毒2(SARS-CoV-2)对世界产生了巨大影响,迫使医学界迅速有效地寻找管理2019冠状病毒病(COVID-19)的方法。2019冠状病毒病大流行与1981年的人类免疫缺陷病毒大流行有许多相似之处,从害怕治疗我们知之甚少的病毒患者,到分析这两种疾病中CD4+水平是如何受到影响的。经典的情况是,HIV患者的CD4+水平会下降,然而,鉴于我们身体的免疫反应,在活跃的COVID-19感染期间,这些水平也会下降。此外,有推测认为,感染SARS-CoV-2的HIV感染者死亡风险更高。因此,这两种病毒的相互作用会形成一种综合征文化,因此,需要谨慎监测和治疗人类免疫缺陷病毒和COVID-19患者。