Zang Xiaoming, Sun Mi, Xian Jin, Yu Huijuan, Zhang Xin, Zhang Changyun, Tan Qiwen
Shandong University of Traditional Chinese Medicine.
Shandong Provincial Hospital of Traditional Chinese Medicine, Shandong, China.
Medicine (Baltimore). 2020 Nov 20;99(47):e23219. doi: 10.1097/MD.0000000000023219.
Nonalcoholic fatty liver disease (NAFLD) is a multisystem disease, which may develop gradually into nonalcoholic steatohepatitis, liver fibrosis, and cirrhosis. As a classical method of traditional Chinese medicine, acupuncture has been used to treat NAFLD in clinical practice. However, there is no systematic review and meta-analysis of acupuncture on NAFLD. There is an urgent need to evaluate the clinical efficacy of acupuncture for NAFLD.
We will perform a comprehensive retrieval in the following electronic databases: MEDLINE, Embase, Cochrane Library Central Register of Controlled Trials, PubMed, Science Citation Index Expanded (Web of Science), Epistemonikos, China National Knowledge Infrastructure (CNKI) database, Wanfang Data Knowledge Service Platform, Chinese Scientific Journals Database (VIP), Chinese Biomedical Literature Service System (SinoMed), and other databases from their inception to October 2020. We will select the qualified studies for data extraction and assess the quality and risk of bias, independently. The meta-analyses will be conducted by using the RevMan 5.3.
This study will provide a reliable basis for the treatment of NAFLD with acupuncture.
The findings will be an available reference to evaluate whether acupuncture is an effective intervention for patient with NAFLD.
10.17605/OSF.IO/VFYXH.
非酒精性脂肪性肝病（NAFLD）是一种多系统疾病，可能会逐渐发展为非酒精性脂肪性肝炎、肝纤维化和肝硬化。针灸作为中医的经典疗法，已在临床实践中用于治疗NAFLD。然而，目前尚无关于针灸治疗NAFLD的系统评价和荟萃分析。迫切需要评估针灸治疗NAFLD的临床疗效。
我们将在以下电子数据库中进行全面检索：MEDLINE、Embase、Cochrane对照试验中心注册库、PubMed、科学引文索引扩展版（Web of Science）、Epistemonikos、中国知网数据库、万方数据知识服务平台、维普中文科技期刊数据库、中国生物医学文献服务系统（SinoMed）以及其他数据库，检索时间范围从建库至2020年10月。我们将选择合格的研究进行数据提取，并独立评估其质量和偏倚风险。荟萃分析将使用RevMan 5.3软件进行。
本研究将为针灸治疗NAFLD提供可靠依据。
本研究结果将为评估针灸是否为NAFLD患者的有效干预措施提供有用参考。
10.17605/OSF.IO/VFYXH。
