Department of Chemistry, Indraraj Arts, Commerce and Science College, Sillod, Maharashtra, India.
Maulana Azad Arts, Science and Commerce College, Aurangabad, Maharashtra, India.
Nat Prod Res. 2022 Apr;36(8):2177-2181. doi: 10.1080/14786419.2020.1849197. Epub 2020 Nov 23.
Pigeon Pea is a well-received traditional nutritious and medicinal plant in India since ancient times. The plant is identified for its impressive pharmacological activities like antimicrobial, anti-inflammatory, antitubercular, antioxidant, neuroprotective, antihypertensive, antihyperglycemic and anticancer properties. The metabolites from Pigeon Pea leaves methanolic extract were identified using hyphenated instruments namely Gas Chromatography-Mass Spectroscopy (GC-MS) and Liquid Chromatography-Mass Spectroscopic (LC-MS) method. GC and LC chromatogram showed proper separation and presence of several bioactive compounds such as flavonoids, terpenoids, essential oils, alkaloids, and coumarins. LC-MS investigation reported the presence of Selidin (coumarin) and Tamarixetin (monomethoxyflavone) in the Pigeon Pea Leaves. The present investigations have demonstrated that methanolic extract of Pigeon Pea leaves exhibited impressive antibacterial activity against and antifungal activity against with MIC values 50 μg/ml 250 μg/ml respectively. The extracts studied here have demonstrated to be a new remedial source used against diseases caused by these microorganisms.
兵豆是一种自古以来在印度广受欢迎的传统营养和药用植物。该植物具有令人印象深刻的药理学活性，如抗菌、抗炎、抗结核、抗氧化、神经保护、降压、降血糖和抗癌特性。使用串联仪器，即气相色谱-质谱联用仪 (GC-MS) 和液相色谱-质谱联用仪 (LC-MS)，鉴定了兵豆叶甲醇提取物中的代谢物。GC 和 LC 色谱图显示出适当的分离和存在几种生物活性化合物，如类黄酮、萜类、精油、生物碱和香豆素。LC-MS 研究报告了兵豆叶中 Selidin（香豆素）和 Tamarixetin（单甲氧基黄酮）的存在。目前的研究表明，兵豆叶的甲醇提取物对 具有显著的抗菌活性，对 具有抗真菌活性，MIC 值分别为 50μg/ml 和 250μg/ml。研究中的提取物已被证明是一种新的治疗来源，可用于治疗这些微生物引起的疾病。
