Reyes Angel M, Katz Jeffrey N, Schoenfeld Andrew J, Kang James D, Losina Elena, Chang Yuchiao
Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopaedic Surgery, Brigham and Women's Hospital, 60 Fenwood Rd, Boston, MA 02115 USA; Harvard Medical School, 25 Shattuck St, Boston, MA 02115 USA.
Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopaedic Surgery, Brigham and Women's Hospital, 60 Fenwood Rd, Boston, MA 02115 USA; Harvard Medical School, 25 Shattuck St, Boston, MA 02115 USA; Division of Rheumatology, Section of Clinical Sciences, Immunology and Allergy, Brigham and Women's Hospital, 60 Fenwood Rd, Boston, MA 02115 USA; Departments of Epidemiology and Environmental Health, Harvard T.H. Chan School of Public Health, 677 Huntingon Ave, Boston, MA 02115 USA; Department of Orthopaedic Surgery, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115 USA.
Spine J. 2021 May;21(5):785-794. doi: 10.1016/j.spinee.2020.11.003. Epub 2020 Nov 20.
Degenerative lumbar conditions are prevalent, disabling, and frequently managed with decompression and fusion. Black patients have lower spinal fusion rates than White patients.
Determine whether specific lumbar fusion procedure utilization differs by race/ethnicity and whether length of stay (LOS) or inpatient complications differ by race/ethnicity after accounting for procedure performed.
Large database retrospective cohort study PATIENT SAMPLE: Lumbar fusion recipients at least age 50 in the 2016 National Inpatient Sample with diagnoses of degenerative lumbar conditions.
Type of fusion procedure used and inpatient safety measures including LOS, prolonged LOS, inpatient medical and surgical complications, mortality, and cost.
We examined the association between race/ethnicity and the safety measures above. Covariates included several patient and hospital factors. We used multiple linear or logistic regression to determine the association between race and fusion type (PLF, P/TLIF, ALIF, PLF + P/TLIF, and PLF + ALIF [anterior-posterior fusion]) and to determine whether race was associated independently with inpatient safety measures, after adjustment for patient and hospital factors.
Fusion method use did not differ among racial/ethnic groups, except for somewhat lower anterior-posterior fusion utilization in Black patients compared to White patients (crude odds ratio [OR]: 0.81 [0.67-0.97]). Inpatient safety measures differed by race/ethnicity for rates of prolonged LOS (Blacks 18.1%, Hispanics 14.5%, and Whites 11.7%), medical complications (Blacks 9.9%, Hispanics 8.7%, and Whites 7.7%), and surgical complications (Blacks 5.2%, Hispanics 6.9%, and Whites 5.4%). Differences persisted after adjustment for procedure type as well as patient and hospital factors. Blacks and Hispanics had higher risk for prolonged LOS compared to Whites (adjusted OR Blacks 1.39 [95% confidence interval {CI} 1.22-1.59]; Hispanics 1.24 [95% CI 1.02-1.52]). Blacks had higher risk for inpatient medical complications compared to Whites (adjusted OR 1.24 [95% CI 1.05-1.48]), and Hispanics had higher risk for inpatient surgical complications compared to Whites (adjusted OR 1.34 [95% CI 1.06-1.68]).
Fusion method use was generally similar between racial/ethnic groups. Inpatient safety measures, adjusted for procedure type, patient and hospital factors, were worse for Blacks and Hispanics.
退行性腰椎疾病很常见,会导致残疾,通常采用减压和融合手术进行治疗。黑人患者的脊柱融合率低于白人患者。
确定特定的腰椎融合手术的使用情况是否因种族/民族而异,以及在考虑所实施的手术之后,住院时间(LOS)或住院并发症是否因种族/民族而异。
大型数据库回顾性队列研究
2016年全国住院患者样本中年龄至少50岁、诊断为退行性腰椎疾病的腰椎融合手术接受者。
所使用的融合手术类型以及住院安全指标,包括住院时间、延长的住院时间、住院医疗和手术并发症、死亡率及费用。
我们研究了种族/民族与上述安全指标之间的关联。协变量包括多个患者和医院因素。我们使用多元线性或逻辑回归来确定种族与融合类型(后路腰椎融合术[PLF]、经椎间孔腰椎椎体间融合术/后路腰椎椎体间融合术[P/TLIF]、前路腰椎椎体间融合术[ALIF]、PLF + P/TLIF以及PLF + ALIF[前后路融合术])之间的关联,并在对患者和医院因素进行调整之后,确定种族是否与住院安全指标独立相关。
种族/民族群体之间融合手术方法的使用没有差异,只是与白人患者相比,黑人患者的前后路融合术使用率略低(粗比值比[OR]:0.81[0.67 - 0.97])。在延长住院时间率(黑人18.1%,西班牙裔14.5%,白人11.7%)、医疗并发症(黑人9.9%,西班牙裔8.7%,白人7.7%)和手术并发症(黑人5.2%,西班牙裔6.9%,白人5.4%)方面,住院安全指标因种族/民族而异。在对手术类型以及患者和医院因素进行调整之后,差异仍然存在。与白人相比,黑人和西班牙裔延长住院时间的风险更高(调整后的OR,黑人1.39[95%置信区间{CI}1.22 - 1.59];西班牙裔1.24[95%CI 1.02 - 1.52])。与白人相比,黑人发生住院医疗并发症的风险更高(调整后的OR 1.24[95%CI 1.05 - 1.48]),与白人相比,西班牙裔发生住院手术并发症的风险更高(调整后的OR 1.34[95%CI 1.06 - 1.68])。
种族/民族群体之间融合手术方法的使用总体上相似。在对手术类型、患者和医院因素进行调整之后,黑人和西班牙裔的住院安全指标更差。