Department of Chemistry, Technical University of Denmark, Kongens Lyngby 2800, Denmark.
Chem Commun (Camb). 2020 Dec 25;56(99):15589-15592. doi: 10.1039/d0cc07472a. Epub 2020 Nov 27.
A compact antibiotic delivery system based on enzymatic biofuel cells was prepared, in which ampicillin was released when discharged in the presence of glucose and O. The release of ampicillin was effective in inhibiting the growth of bacterium Escherichia coli as confirmed by ex situ and in situ release studies in culture media.
一种基于酶生物燃料电池的紧凑型抗生素输送系统被制备出来,当在葡萄糖和 O 的存在下排出时,氨苄青霉素被释放。通过在培养基中的离体和原位释放研究证实,氨苄青霉素的释放有效地抑制了细菌大肠杆菌的生长。