Wallace Robert Keith
Department of Physiology and Health, Maharishi International University, Fairfield, IA 52556, USA.
Medicina (Kaunas). 2020 Nov 30;56(12):661. doi: 10.3390/medicina56120661.
Within the disciplines of modern medicine, P4 medicine is emerging as a new field which focuses on the whole patient. The development of Ayurgenomics could greatly enrich P4 medicine by providing a clear theoretical understanding of the whole patient and a practical application of ancient and modern preventative and therapeutic practices to improve mental and physical health. One of the most difficult challenges today is understanding the ancient concepts of Ayurveda in terms of modern science. To date, a number of researchers have attempted this task, of which one of the most successful outcomes is the creation of the new field of Ayurgenomics. Ayurgenomics integrates concepts in Ayurveda, such as Prakriti, with modern genetics research. It correlates the combination of three doshas, Vata, Pitta and Kapha, with the expression of specific genes and physiological characteristics. It also helps to interpret Ayurveda as an ancient science of epigenetics which assesses the current state of the doshas, and uses specific personalized diet and lifestyle recommendations to improve a patient's health. This review provides a current update of this emerging field.
在现代医学学科中，个性化预防、预测、参与和精准（P4）医学正在成为一个关注患者整体的新领域。阿育吠陀基因组学的发展可以通过提供对患者整体的清晰理论理解以及对古今预防和治疗方法的实际应用来极大地丰富P4医学，以改善身心健康。当今最艰巨的挑战之一是从现代科学的角度理解阿育吠陀的古老概念。迄今为止，许多研究人员都尝试过这项任务，其中最成功的成果之一就是创建了阿育吠陀基因组学这一新领域。阿育吠陀基因组学将阿育吠陀中的概念，如体质，与现代遗传学研究相结合。它将风、火、水三种生命能量的组合与特定基因的表达和生理特征联系起来。它还有助于将阿育吠陀解释为一门古老的表观遗传学科学，该科学评估生命能量的当前状态，并使用特定的个性化饮食和生活方式建议来改善患者的健康。本综述提供了这个新兴领域的最新进展。
