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Poult Sci. 2020 Oct;99(10):5127-5136. doi: 10.1016/j.psj.2020.06.067. Epub 2020 Jul 24.
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Chemical Composition, Antifungal and Insecticidal Activities of the Essential Oils from Tunisian Subsp. and Subsp. .突尼斯亚种和亚种的精油的化学成分、抗真菌和杀虫活性。
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在兽医学中使用精油对抗细菌和真菌感染。

Use of Essential Oils in Veterinary Medicine to Combat Bacterial and Fungal Infections.

作者信息

Ebani Valentina Virginia, Mancianti Francesca

机构信息

Department of Veterinary Sciences, University of Pisa, Viale delle Piagge 2, 56124 Pisa, Italy.

Interdepartmental Research Center "Nutraceuticals and Food for Health", University of Pisa, Via del Borghetto 80, 56124 Pisa, Italy.

出版信息

Vet Sci. 2020 Nov 30;7(4):193. doi: 10.3390/vetsci7040193.

DOI:10.3390/vetsci7040193
PMID:33266079
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7712454/
Abstract

Essential oils (EOs) are secondary metabolites of plants employed in folk medicine for a long time thanks to their multiple properties. In the last years, their use has been introduced in veterinary medicine, too. The study of the antibacterial properties of EOs is of increasing interest, because therapies with alternative drugs are welcome to combat infections caused by antibiotic-resistant strains. Other issues could be resolved by EOs employment, such as the presence of antibiotic residues in food of animal origin and in environment. Although the in vitro antimicrobial activity of EOs has been frequently demonstrated in studies carried out on bacterial and fungal strains of different origins, there is a lack of information about their effectiveness in treating infections in animals. The scientific literature reports some studies about in vitro EOs' activity against animal clinical bacterial and fungal isolates, but in vivo studies are very scanty. The use of EOs in therapy of companion and farm animals should follow careful studies on the toxicity of these natural products in relation to animal species and route of administration. Moreover, considering the different behavior of EOs in relation to both species and strain pathogen, before starting a therapy, an aromatogram should be executed to choose the oil with the best antimicrobial activity.

摘要

精油(EOs)是植物的次生代谢产物,由于其多种特性,长期以来一直被用于民间医学。近年来,它们也被引入到兽医学中。对精油抗菌特性的研究越来越受到关注,因为使用替代药物的疗法有助于对抗由抗生素耐药菌株引起的感染。使用精油还可以解决其他问题,例如动物源性食品和环境中抗生素残留的问题。尽管在对不同来源的细菌和真菌菌株进行的研究中经常证明精油具有体外抗菌活性,但关于它们在治疗动物感染方面的有效性的信息却很少。科学文献报道了一些关于精油对动物临床细菌和真菌分离株的体外活性的研究,但体内研究非常少。在伴侣动物和农场动物的治疗中使用精油之前,应仔细研究这些天然产物相对于动物物种和给药途径的毒性。此外,考虑到精油相对于物种和病原体菌株的不同行为,在开始治疗之前,应进行芳香图谱分析以选择具有最佳抗菌活性的精油。