Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Nutrition Department, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil.
PLoS One. 2020 Dec 3;15(12):e0243276. doi: 10.1371/journal.pone.0243276. eCollection 2020.
High-intensity functional training (HIFT) has become more popular, and the number of practitioners has increased; however, it remains unclear whether perturbations in the immune parameters occur, even after one single bout. Our aim was to examine acute leucocyte, muscle damage, and stress marker responses following a single 'Cindy' workout session, and compare the results between novice and experienced participants.
Twenty-three HIFT practitioners (age 31.0 ± 1.0 years) completed the 'Cindy' workout. They were categorized as novice (3-8 months of experience; n = 10) and experienced (≥18 months; n = 13). White blood cell (WBC) count, plasma creatine kinase (CK) activity, blood cortisol level, and lactate concentration were measured. Blood analysis was performed before (pre-ex), immediately after (post-ex), 30 min after (post-30 min), and 24 h after (post-24 h) a single 'Cindy' workout session.
WBC count was higher post-ex (6.8 to 11.8x103/μL) and returned to baseline values within post-30 min (p<0.01). Neutrophil (3.3 to 4.5x103/μL) and lymphocyte levels (2.8 to 5.9x103/μL) were higher post-ex and returned to baseline values after post-24 h, yet lymphocytopoenia (2.2x103/μL) was observed at post-30 min (p<0.01). CK increased post-ex (174.9 to 226.7 U.L-1) and remained elevated post-24 h. Cortisol (14.7 to 17.0 μg/dL) and lactate (1.9 to 13.5 mmol.l-1) responses increased post-ex, but only the lactate level was reduced at post-30 min (p<0.01). The experienced participants had higher WBC, lymphocyte, and cortisol concentrations post-ex than the novice ones (p<0.01).
A single HIFT session elicited significant acute perturbations in WBC count, stress markers, and muscle tissue, which is like other similar regimens. Importantly, the experienced participants showed greater lymphocyte and cortisol responses than the novice ones.
高强度功能训练（HIFT）越来越受欢迎，从业者的数量也在增加；然而，目前尚不清楚单次训练是否会导致免疫参数发生变化，即使是单次训练也是如此。我们的目的是研究单次“辛迪”训练后白细胞、肌肉损伤和应激标志物的急性反应，并比较新手和经验丰富的参与者之间的结果。
23 名 HIFT 从业者（年龄 31.0 ± 1.0 岁）完成了“辛迪”训练。他们被分为新手（3-8 个月的经验；n = 10）和经验丰富的（≥18 个月；n = 13）。白细胞（WBC）计数、血浆肌酸激酶（CK）活性、皮质醇水平和乳酸浓度均进行了测量。在单次“辛迪”训练前（pre-ex）、后即刻（post-ex）、后 30 分钟（post-30 min）和后 24 小时（post-24 h）进行血液分析。
白细胞计数在 post-ex 时更高（6.8 至 11.8x103/μL），并在 post-30 min 时恢复到基线值（p<0.01）。中性粒细胞（3.3 至 4.5x103/μL）和淋巴细胞水平（2.8 至 5.9x103/μL）在 post-ex 时更高，并在 post-24 h 后恢复到基线值，但在 post-30 min 时观察到淋巴细胞减少症（2.2x103/μL）（p<0.01）。CK 在 post-ex 时增加（174.9 至 226.7 U.L-1），并在 post-24 h 时仍保持升高。皮质醇（14.7 至 17.0 μg/dL）和乳酸（1.9 至 13.5 mmol.l-1）反应在 post-ex 时增加，但只有乳酸水平在 post-30 min 时降低（p<0.01）。经验丰富的参与者在 post-ex 时的白细胞、淋巴细胞和皮质醇浓度高于新手（p<0.01）。
单次 HIFT 训练会引起白细胞计数、应激标志物和肌肉组织的显著急性变化，与其他类似的训练方案相似。重要的是，经验丰富的参与者的淋巴细胞和皮质醇反应大于新手。
