J Phys Act Health. 2021 Jan 1;18(1):76-85. doi: 10.1123/jpah.2020-0525. Epub 2020 Dec 4.
In 2020, the World Health Organization (WHO) released global guidelines on physical activity (PA) and sedentary behavior, for the first time providing population-based recommendations for people living with selected chronic conditions. This article briefly presents the guidelines, related processes and evidence, and, importantly, considers how they may be used to support research, practice, and policy.
A brief overview of the scope, agreed methods, selected chronic conditions (adults living with cancer, hypertension, type 2 diabetes, and human immunodeficiency virus), and appraisal of systematic review evidence on PA/sedentary behavior is provided. Methods were consistent with World Health Organization protocols for developing guidelines.
Moderate to high certainty evidence (varying by chronic condition and outcome examined) supported that PA can reduce the risk of disease progression or premature mortality and improve physical function and quality of life in adults living with chronic conditions. Direct evidence on sedentary behavior was lacking; however, evidence extrapolated from adult populations was considered applicable, safe, and likely beneficial (low certainty due to indirectness).
Clinical and public health professionals and policy makers should promote the World Health Organization 2020 global guidelines and develop and implement services and programs to increase PA and limit sedentary behavior in adults living with chronic conditions.
2020 年，世界卫生组织（WHO）发布了全球体力活动和久坐行为指南，首次为患有特定慢性病的人群提供了基于人群的建议。本文简要介绍了这些指南、相关过程和证据，重要的是，还考虑了如何将这些指南用于支持研究、实践和政策。
本文简要概述了指南的范围、商定的方法、特定慢性病（患有癌症、高血压、2 型糖尿病和人类免疫缺陷病毒的成年人），以及对体力活动/久坐行为的系统评价证据进行评估。方法与世界卫生组织制定指南的协议一致。
有中等至高度确定性证据（因所检查的慢性病和结局而异）支持体力活动可以降低疾病进展或过早死亡的风险，并改善患有慢性病的成年人的身体功能和生活质量。关于久坐行为的直接证据缺乏；然而，从成年人群中推断出的证据被认为是适用、安全且可能有益的（由于间接性，确定性为低）。
临床和公共卫生专业人员以及政策制定者应推广世界卫生组织 2020 年全球指南，并制定和实施服务和计划，以增加患有慢性病的成年人的体力活动并限制其久坐行为。
