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经颅电刺激:治疗精神疾病的临床意义与实践

Transcranial Electrical Stimulation: Clinical Implication and Practice for Treatment of Psychiatric Illness.

作者信息

Yang Chaeyeon, Jung Bori, Lee Seung-Hwan

机构信息

Clinical Emotion and Cognition Research Laboratory, Inje University, Goyang, Korea.

Department of Psychology, Sogang University, Seoul, Korea.

出版信息

Clin Psychopharmacol Neurosci. 2024 Aug 31;22(3):391-404. doi: 10.9758/cpn.23.1118. Epub 2023 Sep 11.

DOI:10.9758/cpn.23.1118
PMID:39069679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11289600/
Abstract

Brain electrical stimulation, particularly non-invasive brain stimulation (NIBS) techniques such as transcranial electrical stimulation (tES), have emerged as a promising treatment for various psychiatric disorders, including depression, anxiety, and post-traumatic stress disorder. tES techniques, such as transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), and transcranial random noise stimulation (tRNS), are cost-effective and safe interventions that are designed to affect neuronal circuits in the brain using various modalities. Although tES has shown effectiveness in the treatment of psychiatric disorders, there is a lack of comprehensive papers that consider its clinical implications. Therefore, this review aims to evaluate the clinical implications of tES and provide practical guidance for the treatment of psychiatric illnesses. Moreover, this review provides an overview of tES techniques and their mechanisms of action and summarizes recent clinical studies that have examined the use of tES for psychiatric disorders.

摘要

脑电刺激,尤其是非侵入性脑刺激(NIBS)技术,如经颅电刺激(tES),已成为治疗各种精神疾病的一种有前景的方法,这些精神疾病包括抑郁症、焦虑症和创伤后应激障碍。tES技术,如经颅直流电刺激(tDCS)、经颅交流电刺激(tACS)和经颅随机噪声刺激(tRNS),是具有成本效益且安全的干预措施,旨在通过各种方式影响大脑中的神经回路。尽管tES已显示出对精神疾病治疗的有效性,但缺乏考虑其临床意义的综合性论文。因此,本综述旨在评估tES的临床意义,并为精神疾病的治疗提供实用指导。此外,本综述概述了tES技术及其作用机制,并总结了最近研究tES用于精神疾病治疗的临床研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a62/11289600/4a410b619241/cpn-22-3-391-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a62/11289600/4cfcd7be3510/cpn-22-3-391-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a62/11289600/6ced0c6e432b/cpn-22-3-391-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a62/11289600/4a410b619241/cpn-22-3-391-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a62/11289600/4cfcd7be3510/cpn-22-3-391-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a62/11289600/6ced0c6e432b/cpn-22-3-391-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a62/11289600/4a410b619241/cpn-22-3-391-f3.jpg

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本文引用的文献

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2
Effect of Home-based Self-administered Transcranial Direct Stimulation in Patients with Mild to Moderate Major Depressive Disorder: A Single-arm, Multicentral Trial.家庭自我管理经颅直流电刺激对轻至中度重度抑郁症患者的影响:一项单臂多中心试验
Clin Psychopharmacol Neurosci. 2023 May 30;21(2):271-278. doi: 10.9758/cpn.2023.21.2.271.
3
The impact of gamma transcranial alternating current stimulation (tACS) on cognitive and memory processes in patients with mild cognitive impairment or Alzheimer's disease: A literature review.
伽马经颅交流电刺激(tACS)对轻度认知障碍或阿尔茨海默病患者认知和记忆过程的影响:文献综述。
Brain Stimul. 2023 May-Jun;16(3):748-755. doi: 10.1016/j.brs.2023.04.001. Epub 2023 Apr 5.
4
Cognitive and Neuropathophysiological Outcomes of Gamma-tACS in Dementia: A Systematic Review.伽马经颅交流电刺激在痴呆中的认知和神经病理生理学结果:系统评价。
Neuropsychol Rev. 2024 Mar;34(1):338-361. doi: 10.1007/s11065-023-09589-0. Epub 2023 Mar 6.
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