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严重急性呼吸综合征冠状病毒2(SARS-CoV-2)对拉丁美洲痴呆症的影响:呼吁制定紧急区域计划并采取协调应对措施。

The impact of SARS-CoV-2 in dementia across Latin America: A call for an urgent regional plan and coordinated response.

作者信息

Ibanez Agustin, Santamaria-Garcia Hernando, Guerrero Barragan Alejandra, Kornhuber Alexander, Ton Alyne Mendonca Marques, Slachevsky Andrea, Teixeira Antonio Lucio, Mar Meza Beatriz Marcela, Serrano Cecilia M, Cano Carlos, Arias Gonzalez Carolina, Gonzalez-Billault Christian, Butler Christopher, Bustin Julian, Duran-Aniotz Claudia, Acosta Daisy, Matallana Diana L, Acosta-Alvear Diego, Trépel Dominic, Resende Elisa De Paula França, de Oliveira Fabricio Ferreira, Ibanez Francisco, De Felice Fernanda G, Navarrete Gorka, Tarnanas Ioannis, Meier Irene B, Smid Jerusa, Llibre-Guerra Jorge, Llibre-Rodriguez Juan J, Fajersztajn Laís, Takada Leonel Tadao, Duque Lissette, Okada de Oliveira Maira, Bicalho Maria Aparecida Camargos, Behrens María Isabel, Pintado-Caipa Maritza, Parra Mario, Wilson Maxwell Z, De La Cruz Puebla Myriam, Custodio Nilton, Santibanez Rodrigo, Serafim Rodrigo Bernardo, Tavares Ronnielly Melo, Piña Escudero Stefanie Danielle, Leon Rodriguez Tomas, Dawson Walter, Miller Bruce L, Kosik Kenneth S

机构信息

Global Brain Health Institute (GBHI) University of California San Francisco (UCSF) San Francisco California USA.

Cognitive Neuroscience Center (CNC) Universidad de San Andrés Buenos Aires Argentina.

出版信息

Alzheimers Dement (N Y). 2020 Nov 23;6(1):e12092. doi: 10.1002/trc2.12092. eCollection 2020.

DOI:10.1002/trc2.12092
PMID:33283036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7683959/
Abstract

The SARS-CoV-2 global pandemic will disproportionately impact countries with weak economies and vulnerable populations including people with dementia. Latin American and Caribbean countries (LACs) are burdened with unstable economic development, fragile health systems, massive economic disparities, and a high prevalence of dementia. Here, we underscore the selective impact of SARS-CoV-2 on dementia among LACs, the specific strain on health systems devoted to dementia, and the subsequent effect of increasing inequalities among those with dementia in the region. Implementation of best practices for mitigation and containment faces particularly steep challenges in LACs. Based upon our consideration of these issues, we urgently call for a coordinated action plan, including the development of inexpensive mass testing and multilevel regional coordination for dementia care and related actions. Brain health diplomacy should lead to a shared and escalated response across the region, coordinating leadership, and triangulation between governments and international multilateral networks.

摘要

严重急性呼吸综合征冠状病毒2(SARS-CoV-2)全球大流行将对经济薄弱国家以及包括痴呆症患者在内的弱势群体产生尤为严重的影响。拉丁美洲和加勒比地区国家(LACs)面临着经济发展不稳定、卫生系统脆弱、巨大的经济差距以及痴呆症高患病率等问题。在此,我们强调SARS-CoV-2对拉丁美洲和加勒比地区国家痴呆症患者的选择性影响、对致力于痴呆症治疗的卫生系统的特殊压力,以及该地区痴呆症患者之间不平等加剧的后续影响。在拉丁美洲和加勒比地区国家,实施缓解和控制的最佳做法面临着尤为严峻的挑战。基于对这些问题的考虑,我们紧急呼吁制定一项协调一致的行动计划,包括开展低成本的大规模检测以及针对痴呆症护理和相关行动的多层次区域协调。脑健康外交应促成整个地区共同且力度更大的应对措施,协调领导工作,并在政府与国际多边网络之间形成三角协作关系。

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本文引用的文献

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Alzheimers Dement. 2021 Feb;17(2):295-313. doi: 10.1002/alz.12202. Epub 2020 Nov 20.
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A Scalable, Easy-to-Deploy Protocol for Cas13-Based Detection of SARS-CoV-2 Genetic Material.一种用于基于Cas13检测SARS-CoV-2遗传物质的可扩展、易于部署的协议。
J Clin Microbiol. 2021 Mar 19;59(4). doi: 10.1128/JCM.02402-20.
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A Fast and Accessible Method for the Isolation of RNA, DNA, and Protein To Facilitate the Detection of SARS-CoV-2.
新冠病毒感染后对秘鲁成年人认知能力的影响。
Front Psychol. 2024 Jun 25;15:1325237. doi: 10.3389/fpsyg.2024.1325237. eCollection 2024.
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Walking the talk for dementia: A unique immersive, embodied, and multi-experiential initiative.践行痴呆症防治:一项独特的沉浸式、体验式和多感官体验计划。
Alzheimers Dement. 2024 Mar;20(3):2309-2322. doi: 10.1002/alz.13644. Epub 2024 Jan 26.
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Prevalence of post-traumatic stress disorder risk post-COVID-19 in 12 countries in Latin America: a cross-sectional survey.新冠后(post-COVID-19)在拉丁美洲 12 个国家的创伤后应激障碍风险的流行率:一项横断面调查。
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The BrainLat project, a multimodal neuroimaging dataset of neurodegeneration from underrepresented backgrounds.BrainLat 项目,一个来自代表性不足背景的神经退行性变的多模态神经影像学数据集。
Sci Data. 2023 Dec 9;10(1):889. doi: 10.1038/s41597-023-02806-8.
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The Brain Health Diplomat's Toolkit: supporting brain health diplomacy leaders in Latin America and the Caribbean.《大脑健康外交官工具包:支持拉丁美洲和加勒比地区的大脑健康外交领导者》
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