Wang Xue-Song, Li Jia-Jia, Wang Yue-Shen, Yu Chao-Chao, He Chuan, Huang Zhong-Sheng, Wu Miao, Kong Li-Hong
Hubei University of Chinese Medicine.
Preventive Treatment of Acupuncture and Moxibustion of Hubei Provincial Collaborative Innovation Center, Wuhan, Hubei.
Medicine (Baltimore). 2020 Dec 4;99(49):e23548. doi: 10.1097/MD.0000000000023548.
To compare and rank the clinical effects of different acupuncture and acupuncture-related therapies on patients with hyperlipidemia.
We used Network Meta-Analysis (NMA) to evaluate the direct and indirect evidence from relevant studies. Three English and 4 Chinese databases were searched to collect randomized controlled trials (RCT) of acupuncture and related therapies in the treatment of hyperlipidemia. The data were analyzed using Stata15.0 and WinBUGS1.4.3 software after 2 researchers independently screened the literature, extracted the data, and assessed the risk of bias in the included studies.
Based on the current evidence, we comprehensively compare the pros and cons of various acupuncture-related therapies, rank the efficacy of various acupuncture-related therapies compared with statins in the treatment of hyperlipidemia, and summarize the best acupuncture intervention methods or combinations.
This study will provide new evidence for the safety and effectiveness of acupuncture-related therapies in the treatment of hyperlipidemia, and may be helpful for clinicians, hyperlipidemia patients, and clinical guideline makers to choose the optimal combination of acupuncture for the treatment of hyperlipidemia.
INPLASY2020100100.
比较并排序不同针灸及与针灸相关疗法对高脂血症患者的临床疗效。
我们采用网状Meta分析（NMA）来评估相关研究的直接和间接证据。检索了3个英文数据库和4个中文数据库，以收集针灸及相关疗法治疗高脂血症的随机对照试验（RCT）。在2名研究人员独立筛选文献、提取数据并评估纳入研究的偏倚风险后，使用Stata15.0和WinBUGS1.4.3软件对数据进行分析。
基于当前证据，我们全面比较了各种与针灸相关疗法的优缺点，对各种与针灸相关疗法与他汀类药物相比治疗高脂血症的疗效进行排序，并总结出最佳的针灸干预方法或组合。
本研究将为与针灸相关疗法治疗高脂血症的安全性和有效性提供新的证据，可能有助于临床医生、高脂血症患者及临床指南制定者选择治疗高脂血症的最佳针灸组合。
INPLASY2020100100。
