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土耳其布尔萨成年人的维生素 D 状况。

Vitamin D status in the adult population of Bursa-Turkey.

机构信息

Family Practice Unit, Uludağ University Family Health Center, Bursa, Turkey.

Department of Internal Medicine, Division of Endocrinology and Metabolism, Uludağ University Faculty of Medicine, Bursa, Turkey.

出版信息

Eur J Gen Pract. 2020 Dec;26(1):156-162. doi: 10.1080/13814788.2020.1846712.

Abstract

BACKGROUND

Vitamin D, along with parathyroid hormone (PTH) and calcitonin, is an important hormone that affects bone and calcium metabolism.

OBJECTIVES

To evaluate the vitamin D status and its seasonal variation in the adult population of Bursa.

METHODS

Since there is not enough information about vitamin D levels, 25 OH vitamin D levels were analysed retrospectively from the records of 11,734 adult subjects (9142 women, 2592 men) admitted to 24 family health centres located in different districts of Bursa between 1 December 2017 and 30 November 2018. Some tests that can affect vitamin D levels, demographic features, and accompanying comorbidities were also evaluated. A face-to-face questionnaire was administered to subjects who were willing to answer ( = 2965).

RESULTS

The mean serum vitamin D level was 16.6 ± 11.5 ng/mL in the entire population, 15.8 ± 11.7 ng/mL in women and 19.5 ± 9.9 ng/mL in men. The percentage of subjects with a vitamin D level <20 ng/mL was highest in March-May and lowest in the September-November period (80.7% and 69.9% for women, 77.5% and 32.9% for men, respectively).

CONCLUSION

Vitamin D levels <20 ng/mL are more prominent in women, and decline in spring, in the adult population of Bursa. These results are meaningful for the population living in Bursa, Turkey and the northern European region.

摘要

背景

维生素 D 与甲状旁腺激素(PTH)和降钙素一起,是影响骨骼和钙代谢的重要激素。

目的

评估布尔萨成年人群的维生素 D 状况及其季节性变化。

方法

由于缺乏关于维生素 D 水平的足够信息,我们回顾性地分析了 2017 年 12 月 1 日至 2018 年 11 月 30 日期间在布尔萨不同地区的 24 个家庭健康中心就诊的 11734 名成年患者(9142 名女性,2592 名男性)的记录中的 25-羟维生素 D 水平。还评估了可能影响维生素 D 水平的一些检测、人口统计学特征和并存的合并症。我们对愿意回答问题的患者进行了面对面的问卷调查( = 2965)。

结果

在整个人群中,血清维生素 D 水平的平均值为 16.6 ± 11.5 ng/mL,女性为 15.8 ± 11.7 ng/mL,男性为 19.5 ± 9.9 ng/mL。维生素 D 水平<20 ng/mL 的患者百分比在 3 月至 5 月最高,9 月至 11 月最低(女性分别为 80.7%和 69.9%,男性分别为 77.5%和 32.9%)。

结论

在布尔萨成年人群中,维生素 D 水平<20 ng/mL 的情况在女性中更为突出,并在春季下降。这些结果对居住在土耳其布尔萨和北欧地区的人群具有重要意义。

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