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自闭症谱系障碍特征选择与分类的机器学习方法综述

A Review of Machine Learning Methods of Feature Selection and Classification for Autism Spectrum Disorder.

作者信息

Rahman Md Mokhlesur, Usman Opeyemi Lateef, Muniyandi Ravie Chandren, Sahran Shahnorbanun, Mohamed Suziyani, Razak Rogayah A

机构信息

Center for Cyber Security, Faculty of Information Science and Technology, Universiti Kebangsaan Malaysia, Bangi 43600 UKM, Selangor, Malaysia.

Center for Artificial Intelligence Technology, Faculty of Information Science and Technology, Universiti Kebangsaan Malaysia, Bangi 43600 UKM, Selangor, Malaysia.

出版信息

Brain Sci. 2020 Dec 7;10(12):949. doi: 10.3390/brainsci10120949.

Abstract

Autism Spectrum Disorder (ASD), according to DSM-5 in the American Psychiatric Association, is a neurodevelopmental disorder that includes deficits of social communication and social interaction with the presence of restricted and repetitive behaviors. Children with ASD have difficulties in joint attention and social reciprocity, using non-verbal and verbal behavior for communication. Due to these deficits, children with autism are often socially isolated. Researchers have emphasized the importance of early identification and early intervention to improve the level of functioning in language, communication, and well-being of children with autism. However, due to limited local assessment tools to diagnose these children, limited speech-language therapy services in rural areas, etc., these children do not get the rehabilitation they need until they get into compulsory schooling at the age of seven years old. Hence, efficient approaches towards early identification and intervention through speedy diagnostic procedures for ASD are required. In recent years, advanced technologies like machine learning have been used to analyze and investigate ASD to improve diagnostic accuracy, time, and quality without complexity. These machine learning methods include artificial neural networks, support vector machines, a priori algorithms, and decision trees, most of which have been applied to datasets connected with autism to construct predictive models. Meanwhile, the selection of features remains an essential task before developing a predictive model for ASD classification. This review mainly investigates and analyzes up-to-date studies on machine learning methods for feature selection and classification of ASD. We recommend methods to enhance machine learning's speedy execution for processing complex data for conceptualization and implementation in ASD diagnostic research. This study can significantly benefit future research in autism using a machine learning approach for feature selection, classification, and processing imbalanced data.

摘要

根据美国精神病学协会的《精神疾病诊断与统计手册》第五版(DSM-5),自闭症谱系障碍(ASD)是一种神经发育障碍,其特征包括社交沟通和社交互动缺陷,以及存在局限的重复行为。患有ASD的儿童在共同注意和社交互惠方面存在困难,难以使用非语言和语言行为进行交流。由于这些缺陷,自闭症儿童往往在社交上孤立。研究人员强调了早期识别和早期干预对于提高自闭症儿童语言、沟通和幸福感功能水平的重要性。然而,由于当地诊断这些儿童的评估工具有限,农村地区言语治疗服务有限等原因,这些儿童直到七岁进入义务教育阶段才获得所需的康复治疗。因此,需要通过针对ASD的快速诊断程序来实现早期识别和干预的有效方法。近年来,机器学习等先进技术已被用于分析和研究ASD,以提高诊断准确性、缩短诊断时间并提升诊断质量,且无需复杂操作。这些机器学习方法包括人工神经网络、支持向量机、先验算法和决策树,其中大多数已应用于与自闭症相关的数据集以构建预测模型。同时,在为ASD分类开发预测模型之前,特征选择仍然是一项重要任务。本综述主要调查和分析关于机器学习方法在ASD特征选择和分类方面的最新研究。我们推荐一些方法,以增强机器学习在处理复杂数据时的快速执行能力,以便在ASD诊断研究中进行概念化和实施。这项研究对于未来使用机器学习方法进行自闭症特征选择、分类和处理不平衡数据的研究具有显著益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeaf/7762227/a1f584197eae/brainsci-10-00949-g001.jpg

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