Tavares Alda, Mesquita Alexandra
Department of Medical Oncology, Hospital Pedro Hispano, Matosinhos Local Health Unit of Matosinhos, Matosinhos, Portugal.
Porto Biomed J. 2020 Jun 4;5(3):e65. doi: 10.1097/j.pbj.0000000000000065. eCollection 2020 May-Jun.
At diagnosis, approximately 50% of cases of adenocarcinoma of the pancreas are metastasized and 5-year survival is only 2.9%. We reported a case of a 63-year-old woman with pancreatic adenocarcinoma with multiple hepatic and intra-abdominal metastases that progressed on 2 lines of chemotherapy. She has been under treatment with third-line chemotherapy for 19 months with stable disease and excellent performance status. She has an overall survival of 29 months. There are just a few cases of metastatic disease with long survival described in the literature. The functional status and the good tolerance to treatment may be determinants of prognosis.
在诊断时，胰腺腺癌病例中约50%已发生转移，5年生存率仅为2.9%。我们报告了一例63岁女性胰腺腺癌患者，伴有多处肝转移和腹腔内转移，接受了2线化疗后病情仍进展。她接受三线化疗已19个月，病情稳定，身体状况良好。她的总生存期为29个月。文献中报道的发生转移但生存期长的病例很少。功能状态和对治疗的良好耐受性可能是预后的决定因素。
