• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

2型糖尿病患者的代谢综合征:当前证据综述

Metabolic syndrome in type 2 diabetic patients: a review of current evidence.

作者信息

Regufe Virgínia M G, Pinto Cristina M C B, Perez Pedro M V H C

机构信息

São João University Hospital Center.

Department of Medicine, Faculty of Medicine, University of Porto.

出版信息

Porto Biomed J. 2020 Dec 3;5(6):e101. doi: 10.1097/j.pbj.0000000000000101. eCollection 2020 Nov-Dec.

DOI:10.1097/j.pbj.0000000000000101
PMID:33299950
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7721212/
Abstract

The metabolic syndrome (MS) is a set of metabolic disturbances, represented by various cardiovascular risk factors which are generally associated with the central accumulation of fat and the resistance to insulin. Inadequate changes in eating behaviours and weight loss, which are associated to taking part in regular physical activity, are considered to be primary and first choice therapies for the treatment of MS, as they assist in the reduction of the abdominal girth and visceral fat, improve the sensibility to insulin and reduce the plasmatic concentrations of glucose and triglycerides, raise the values of high density lipoproteins and, consequently decrease the risk factors which contribute to the development of type 2 diabetes. The MS is a current discussion theme in the health field as it is related to illnesses/diseases, which not only cause a worldwide high mortality rate but show increasing incidence. Type 2 diabetes is characterised by a deregulation of the carbohydrates, lipids and proteins found in the metabolism and result in diminished secretion of insulin, resistance to insulin or a combination of both. Type 2 diabetes is the most form of diabetes of the first 3 types of diabetes, representing 90% of all cases. Diabetes is a chronic and complex disease which requires a strict medical follow-up so as to reduce the risks and obtain strategies for its control. The fast-epidemiological global evolution which has been registered in the last few years, leads to it being considered one of the pandemics of the 21st century. In this non-systematic and advanced review of the MS in type 2 diabetic patients, several articles were consulted, and some recently published studies were analysed.

摘要

代谢综合征(MS)是一组代谢紊乱,由各种心血管危险因素表征,这些因素通常与脂肪的中心性堆积和胰岛素抵抗有关。饮食行为和体重减轻方面的改变不足,而这与参与规律的体育活动相关,被认为是治疗MS的主要和首选疗法,因为它们有助于减少腹围和内脏脂肪,提高胰岛素敏感性,降低血糖和甘油三酯的血浆浓度,提高高密度脂蛋白水平,从而降低促成2型糖尿病发生的危险因素。MS是健康领域当前的一个讨论主题,因为它与一些疾病相关,这些疾病不仅在全球造成高死亡率,而且发病率呈上升趋势。2型糖尿病的特征是代谢中碳水化合物、脂质和蛋白质的调节失控,导致胰岛素分泌减少、胰岛素抵抗或两者兼而有之。2型糖尿病是前三种糖尿病类型中最常见的形式,占所有病例的90%。糖尿病是一种慢性复杂疾病,需要严格的医学随访,以降低风险并获得控制策略。过去几年中记录的快速全球流行病学演变,使其被视为21世纪的大流行病之一。在本次对2型糖尿病患者MS的非系统性高级综述中,查阅了多篇文章,并分析了一些最近发表的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f53/7721212/d0d0f6937f3f/pj9-5-e101-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f53/7721212/b2c830c17755/pj9-5-e101-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f53/7721212/bad94b013eb8/pj9-5-e101-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f53/7721212/d0d0f6937f3f/pj9-5-e101-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f53/7721212/b2c830c17755/pj9-5-e101-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f53/7721212/bad94b013eb8/pj9-5-e101-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f53/7721212/d0d0f6937f3f/pj9-5-e101-g003.jpg

相似文献

1
Metabolic syndrome in type 2 diabetic patients: a review of current evidence.2型糖尿病患者的代谢综合征:当前证据综述
Porto Biomed J. 2020 Dec 3;5(6):e101. doi: 10.1097/j.pbj.0000000000000101. eCollection 2020 Nov-Dec.
2
[Pharmacological therapy of obesity].[肥胖症的药物治疗]
G Ital Cardiol (Rome). 2008 Apr;9(4 Suppl 1):83S-93S.
3
[Schizophrenia, diabetes mellitus and antipsychotics].[精神分裂症、糖尿病与抗精神病药物]
Encephale. 2004 Jul-Aug;30(4):382-91. doi: 10.1016/s0013-7006(04)95452-8.
4
Exercise training in obese diabetic patients. Special considerations.肥胖糖尿病患者的运动训练。特殊注意事项。
Sports Med. 1992 Sep;14(3):171-89. doi: 10.2165/00007256-199214030-00004.
5
6
Beyond low-density lipoprotein: addressing the atherogenic lipid triad in type 2 diabetes mellitus and the metabolic syndrome.超越低密度脂蛋白:应对2型糖尿病和代谢综合征中的致动脉粥样硬化脂质三联征。
Am J Cardiovasc Drugs. 2005;5(6):379-87. doi: 10.2165/00129784-200505060-00005.
7
Pharmacodynamic effects of oral contraceptive steroids on biochemical markers for arterial thrombosis. Studies in non-diabetic women and in women with insulin-dependent diabetes mellitus.口服避孕甾体激素对动脉血栓形成生化标志物的药效学作用。非糖尿病女性和胰岛素依赖型糖尿病女性的研究。
Dan Med Bull. 2002 Feb;49(1):43-60.
8
Statins and diabetes.他汀类药物与糖尿病
Semin Vasc Med. 2004 Nov;4(4):321-32. doi: 10.1055/s-2004-869589.
9
What is the relationship between exercise and metabolic abnormalities? A review of the metabolic syndrome.运动与代谢异常之间的关系是什么?代谢综合征综述。
Sports Med. 2004;34(6):371-418. doi: 10.2165/00007256-200434060-00004.
10
[Cardiovascular risk factors and prevention in women: similarities and differences].[女性心血管危险因素与预防:异同]
Ital Heart J Suppl. 2001 Feb;2(2):125-41.

引用本文的文献

1
Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications.连接2型糖尿病与心血管并发症的免疫失调
Life (Basel). 2025 Aug 5;15(8):1241. doi: 10.3390/life15081241.
2
The effectiveness of a self-efficacy enhancement program on health behaviors and clinical outcomes in people with metabolic syndrome: A quasi-experimental study in Thailand.自我效能增强计划对代谢综合征患者健康行为和临床结局的有效性:泰国的一项准实验研究。
Belitung Nurs J. 2025 Aug 3;11(4):432-442. doi: 10.33546/bnj.3891. eCollection 2025.
3
Revealing the regulatory role of lncRNAs SNHG1 and CRNDE on Th17/Treg imbalance in diabetic kidney disease.

本文引用的文献

1
Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9 edition.2019 年全球及各区域糖尿病患病率估算值及 2030 年和 2045 年预测值:国际糖尿病联盟糖尿病地图集(第 9 版)的结果。
Diabetes Res Clin Pract. 2019 Nov;157:107843. doi: 10.1016/j.diabres.2019.107843. Epub 2019 Sep 10.
2
Diabetes and cardiovascular disease: Epidemiology, biological mechanisms, treatment recommendations and future research.糖尿病与心血管疾病:流行病学、生物学机制、治疗建议及未来研究
World J Diabetes. 2015 Oct 10;6(13):1246-58. doi: 10.4239/wjd.v6.i13.1246.
3
揭示长链非编码RNA SNHG1和CRNDE对糖尿病肾病中Th17/Treg失衡的调控作用。
Clin Exp Med. 2025 Aug 2;25(1):271. doi: 10.1007/s10238-025-01802-z.
4
Effects of Conocarpus lancifolius and crocin on superoxide dismutase and protein kinase B genes and protein expressions in diabetic rats.海榄雌和藏红花素对糖尿病大鼠超氧化物歧化酶及蛋白激酶B基因和蛋白表达的影响。
PLoS One. 2025 Jun 26;20(6):e0326676. doi: 10.1371/journal.pone.0326676. eCollection 2025.
5
Can self-rated health be useful to primary care physicians as a diagnostic indicator of metabolic dysregulations amongst patients with type 2 diabetes? A population-based study.自我评估健康状况对基层医疗医生而言能否作为2型糖尿病患者代谢失调的诊断指标?一项基于人群的研究。
BMC Prim Care. 2025 May 16;26(1):171. doi: 10.1186/s12875-024-02671-3.
6
Identification of potential crucial genes and mechanisms associated with metabolically unhealthy obesity based on the gene expression profile.基于基因表达谱鉴定与代谢不健康肥胖相关的潜在关键基因和机制。
Front Genet. 2025 May 1;16:1540721. doi: 10.3389/fgene.2025.1540721. eCollection 2025.
7
The role of changes in metabolic syndrome status on health-related quality of life in Bogor City, West Java, Indonesia: A cross-sectional study.印度尼西亚西爪哇省茂物市代谢综合征状态变化对健康相关生活质量的作用:一项横断面研究。
Belitung Nurs J. 2025 Apr 19;11(2):172-185. doi: 10.33546/bnj.3543. eCollection 2025.
8
Exploring the significance of phase angle in diabetes management: a narrative review.探索相位角在糖尿病管理中的意义:一项叙述性综述。
Diabetol Int. 2025 Feb 8;16(2):223-236. doi: 10.1007/s13340-024-00790-x. eCollection 2025 Apr.
9
New Markers for the Assessment of Microvascular Complications in Patients with Metabolic Syndrome.用于评估代谢综合征患者微血管并发症的新标志物
Metabolites. 2025 Mar 10;15(3):184. doi: 10.3390/metabo15030184.
10
Exploring the Role of Ki67 in the Liver of Diabetic Rats.探索Ki67在糖尿病大鼠肝脏中的作用。
Mater Sociomed. 2024;36(4):250-256. doi: 10.5455/msm.2024.36.250-256.
(13) Diabetes care in the hospital, nursing home, and skilled nursing facility.
(13)医院、疗养院及专业护理机构中的糖尿病护理。
Diabetes Care. 2015 Jan;38 Suppl:S80-5. doi: 10.2337/dc15-S016.
4
(2) Classification and diagnosis of diabetes.(2) 糖尿病的分类与诊断。
Diabetes Care. 2015 Jan;38 Suppl:S8-S16. doi: 10.2337/dc15-S005.
5
(9) Microvascular complications and foot care.(9)微血管并发症与足部护理。
Diabetes Care. 2015 Jan;38 Suppl:S58-66. doi: 10.2337/dc15-S012.
6
A comprehensive review on metabolic syndrome.关于代谢综合征的综合综述。
Cardiol Res Pract. 2014;2014:943162. doi: 10.1155/2014/943162. Epub 2014 Mar 11.
7
Global estimates of diabetes prevalence for 2013 and projections for 2035.全球 2013 年糖尿病患病率估计值及 2035 年预测值。
Diabetes Res Clin Pract. 2014 Feb;103(2):137-49. doi: 10.1016/j.diabres.2013.11.002. Epub 2013 Dec 1.
8
Prevalence of metabolic syndrome in Brazilian adults: a systematic review.代谢综合征在巴西成年人中的流行情况:一项系统综述。
BMC Public Health. 2013 Dec 18;13:1198. doi: 10.1186/1471-2458-13-1198.
9
Prevention of type 2 diabetes in subjects with prediabetes and metabolic syndrome treated with phentermine and topiramate extended release.使用缓释苯丁胺和托吡酯治疗的糖尿病前期和代谢综合征患者2型糖尿病的预防。
Diabetes Care. 2014 Apr;37(4):912-21. doi: 10.2337/dc13-1518. Epub 2013 Oct 8.
10
Prevalence and trends of metabolic syndrome in the adult U.S. population, 1999-2010.美国成年人代谢综合征的流行率和趋势,1999-2010 年。
J Am Coll Cardiol. 2013 Aug 20;62(8):697-703. doi: 10.1016/j.jacc.2013.05.064. Epub 2013 Jun 27.