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担忧和失眠是印度 COVID-19 大流行初期抑郁的风险因素。

Worry and insomnia as risk factors for depression during initial stages of COVID-19 pandemic in India.

机构信息

Multimodal Clinical Neuroimaging Laboratory (MCNL), Center for Neurobehavioral Research, Boys Town National Research Hospital, Boys Town, NE, United States of America.

Program for Trauma and Anxiety (PTAC), Center for Neurobehavioral Research, Boys Town National Research Hospital, Boys Town, NE, United States of America.

出版信息

PLoS One. 2020 Dec 10;15(12):e0243527. doi: 10.1371/journal.pone.0243527. eCollection 2020.

Abstract

The biggest nationwide COVID-19 pandemic lockdown worldwide was enforced in India for an initial period of 21-days. Emerging evidence suggests that pandemic situations and associated lockdowns have an adverse impact on sleep and mental health. However, prediction of sleep health from sociodemographic characteristics and the public's worry during the initial stages of the COVID-19 pandemic has not been extensively explored so far. It's also unclear whether sleep outcomes mediate the association between worry and mental health during pandemic situations. A web-survey (N = 391) on sociodemographic characteristics, COVID-19 related worry, sleep health (insomnia and daytime sleepiness), and depression was conducted during the initial 21-days of the COVID-19 stringent lockdown in India. Multiple regression analyses showed that variables, including sex, age, income level, and worry score, contributed to the significant regression equation for insomnia but not for daytime sleepiness. Specifically, the female, younger, lower income, and highly worried populations contributed significantly more than the male, elderly, higher income, and less worried populations, respectively, to the prediction of insomnia. Mediation analyses showed that insomnia, but not daytime sleepiness, fully mediated the relationship between worry score and severity of depressive symptoms. We provide evidence that the female, younger, lower income, and worried populations may be at higher risk for insomnia during pandemic situations. Current evidence gives hope that improving sleep may reduce depressive symptoms during a pandemic situation. This underscores the importance of the implementation of effective public health policies in conjunction with strategical responses to the COVID-19 pandemic.

摘要

全球最大规模的全国性 COVID-19 大流行封锁在印度实施了最初的 21 天。新出现的证据表明,大流行情况和相关封锁对睡眠和心理健康产生不利影响。然而,迄今为止,尚未广泛探讨从社会人口统计学特征预测睡眠健康以及公众在 COVID-19 大流行初期的担忧。睡眠结果是否在大流行情况下调节担忧与心理健康之间的关联也不清楚。在印度 COVID-19 严格封锁的最初 21 天期间,进行了一项关于社会人口统计学特征、与 COVID-19 相关的担忧、睡眠健康(失眠和白天嗜睡)和抑郁的网络调查(N=391)。多元回归分析表明,包括性别、年龄、收入水平和担忧得分在内的变量对失眠的显著回归方程有贡献,但对白天嗜睡没有贡献。具体来说,女性、年轻、低收入和高度担忧的人群比男性、老年人、高收入和低担忧的人群对失眠的预测贡献更大。中介分析表明,失眠而不是白天嗜睡,完全中介了担忧得分与抑郁严重程度之间的关系。我们提供的证据表明,在大流行情况下,女性、年轻、低收入和担忧的人群可能更容易出现失眠。现有证据表明,改善睡眠可能会减轻大流行期间的抑郁症状。这强调了实施有效的公共卫生政策与针对 COVID-19 大流行的战略应对相结合的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c379/7728274/c6496a1b54e0/pone.0243527.g001.jpg

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