Universidad de Santander, Facultad de Ciencias Exactas, Naturales y Agropecuarias, Grupo de Investigación en Ciencias Agropecuarias-GICA, Bucaramanga, Colombia.
Universidad de Santander, Facultad de Ciencias Exactas, Naturales y Agropecuarias, Grupo de Investigación en Ciencias Agropecuarias-GICA, Bucaramanga, Colombia.
Vet Parasitol Reg Stud Reports. 2020 Dec;22:100487. doi: 10.1016/j.vprsr.2020.100487. Epub 2020 Nov 2.
Fasciola hepatica is a trematode parasite with a worldwide distribution that affects mammals, including humans, and is considered a major food safety and public health problem. A research was conducted in three hundred eighty-five livestock farms located in different altitudinal regions of Colombia between February 2017 and March 2018 with the aim to determine the coprological prevalence, seroprevalence (SP) and risk factors associated with liver fluke F. hepatica. A total of 5620 fecal sample were collected from cattle and processed using sedimentation technique. Additionally, 597 blood samples were collected and processed by an ELISA test. The coprological prevalence of F. hepatica in animals and herds was 6.4% and 38.4%, respectively. Regarding the prevalence by municipalities, there was statistical association (P < .05), indicating that the prevalence was higher in those municipalities above 2000 masl (meters above sea level). Regarding risk factors, cattle raised in municipalities at 2000 to 3000 masl showed about 4 (OR = 3.96 [CI95% 3.1-5]; P < .05) times higher probability for infection than those raised at lower altitude. Cattle from 2 to 3 year of age, showed almost 4 times (OR = 3.7[CI95% 2.5-5.4]; P < .05), increased infection risk. Females and dairy breeds showed almost 2 (OR = 1.9 [CI95% 1.3-2.6]; P < .05) and 10 times (OR = 10 [CI95% 7.8-12.8]; P < .05), respectively, increased infection risk. The presence of antibodies anti- F. hepatica (SP = 37.8%; [CI95% 35.8-39.7]; P < .05) in cattle of the region under study is confirmed, which suggests an endemic behavior of this parasitosis. The present study provides current information on the prevalence of F. hepatica in different altitudinal regions of Colombia, and these findings could be useful for designing new holistic control measures for the liver fluke F. hepatica infection.
肝片形吸虫是一种分布广泛的吸虫寄生虫，可感染包括人类在内的哺乳动物，被认为是主要的食品安全和公共卫生问题。2017 年 2 月至 2018 年 3 月，在哥伦比亚不同海拔地区的 385 个牧场进行了一项研究，旨在确定该地区肝片形吸虫的粪便流行率、血清流行率（SP）和相关风险因素。共采集了 5620 份牛粪便样本，采用沉淀技术进行处理。此外，还采集了 597 份血液样本，采用 ELISA 试验进行处理。动物和畜群的肝片形吸虫粪便流行率分别为 6.4%和 38.4%。就各市镇的流行率而言，存在统计学关联（P<.05），表明海拔在 2000 米以上的市镇的流行率更高。就风险因素而言，在海拔 2000 至 3000 米的市镇中饲养的牛的感染概率比在低海拔地区饲养的牛高约 4 倍（OR=3.96[95%CI3.1-5]；P<.05）。2 至 3 岁的牛感染风险增加近 4 倍（OR=3.7[95%CI2.5-5.4]；P<.05）。雌性和乳用品种的感染风险分别增加近 2 倍（OR=1.9[95%CI1.3-2.6]；P<.05）和 10 倍（OR=10[95%CI7.8-12.8]；P<.05）。该地区牛群中存在抗肝片形吸虫抗体（SP=37.8%[95%CI35.8-39.7]；P<.05），表明该寄生虫病呈地方性流行。本研究提供了哥伦比亚不同海拔地区肝片形吸虫流行率的最新信息，这些发现可能有助于设计肝片形吸虫感染的新综合控制措施。
