Su Chuanyou, Zheng Nan, Gao Yanan, Huang Shengnan, Yang Xue, Wang Ziwei, Yang Hongjian, Wang Jiaqi
Ministry of Agriculture-Laboratory of Quality and Safety Risk Assessment for Dairy Products (Beijing), Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
College of Animal Science and Technology, China Agriculture University, Beijing 100193, China.
Foods. 2020 Dec 10;9(12):1839. doi: 10.3390/foods9121839.
In this study, the content of chromium (Cr), arsenic (As), cadmium (Cd) and lead (Pb) in domestic and imported infant formulas from Beijing, China were analyzed using inductively coupled plasma mass spectrometry. The content of Cr, As, Cd and Pb was 2.51-83.80, 0.89-7.87, 0.13-3.58 and 0.36-5.57 μg/kg, respectively. Even though there were no significant differences in toxic elements content between domestic and imported infant formulas, Cd content was slightly lower in domestic samples. The estimated daily intake (EDI), target hazard quotient (THQ) and hazard index (HI) were calculated for infants between 0.5 and 5 y of age. The EDIs were lower than the oral reference doses. THQ of As, Cr, Cd and Pb was 0.027-0.103, 0.024-0.093, 0.0025-0.0090 and 0.0015-0.0046, respectively. HI values were 0.055-0.192 for boys and 0.056-0.209 for girls and were inversely associated with age with a threshold < 1. The non-carcinogenic risk value were in the safe range, indicating that exposure of As, Pb, Cr and Cd from infant formulas do not represent a health risk in China.
本研究采用电感耦合等离子体质谱法分析了中国北京国产和进口婴儿配方奶粉中铬（Cr）、砷（As）、镉（Cd）和铅（Pb）的含量。Cr、As、Cd和Pb的含量分别为2.51 - 83.80、0.89 - 7.87、0.13 - 3.58和0.36 - 5.57μg/kg。尽管国产和进口婴儿配方奶粉中有毒元素含量无显著差异，但国产样品中Cd含量略低。计算了0.5至5岁婴儿的估计每日摄入量（EDI）、目标危害商（THQ）和危害指数（HI）。EDI低于口服参考剂量。As、Cr、Cd和Pb的THQ分别为0.027 - 0.103、0.024 - 0.093、0.0025 - 0.0090和0.0015 - 0.0046。男孩的HI值为0.055 - 0.192，女孩为0.056 - 0.209，且与年龄呈负相关，阈值<1。非致癌风险值在安全范围内，表明在中国婴儿配方奶粉中As、Pb、Cr和Cd的暴露不构成健康风险。
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