State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, P. R. China.
Department of Chemistry, the Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute for Advanced Study, the Hong Kong University of Science and Technology, Kowloon, Hong Kong, China.
Compr Rev Food Sci Food Saf. 2020 Jul;19(4):2297-2329. doi: 10.1111/1541-4337.12591. Epub 2020 Jun 28.
As a global public health problem, food safety has attracted increasing concern. To minimize the risk exposure of food to harmful ingredients, food quality and safety inspection that covers the whole process of "from farm to fork" is much desired. Fluorescent sensing is a promising and powerful screening tool for sensing hazardous substances in food and thus plays a crucial role in promoting food safety assurance. However, traditional fluorphores generally suffer the problem of aggregation-caused quenching (ACQ) effect, which limit their application in food quality and safety inspection. In this regard, luminogens with aggregation-induced emission property (AIEgens) showed large potential in food analysis since AIEgens effectively surmount the ACQ effect with much better detection sensitivity, accuracy, and robustness. In this contribution, we review the latest developments of food safety monitoring by AIEgens, which will focus on the molecular design of AIEgens and their sensing principles. Several examples of AIE-based sensing applications for screening food contaminations are highlighted, and future perspectives and challenges in this emerging field are tentatively elaborated. We hope this review can motivate new research ideas and interest to aid food safety and quality control, and facilitate more collaborative endeavors to advance the state-of-the-art sensing developments and reduce actual translational gap between laboratory research and industrial production.
作为一个全球性的公共卫生问题,食品安全越来越受到关注。为了将食物接触有害成分的风险降至最低,人们非常希望对食品进行全过程的“从农田到餐桌”的质量和安全检测。荧光传感是一种很有前途和强大的用于检测食品中有害物质的筛选工具,因此在促进食品安全保障方面发挥着至关重要的作用。然而,传统荧光团通常存在聚集诱导猝灭(ACQ)效应的问题,这限制了它们在食品质量和安全检测中的应用。在这方面,具有聚集诱导发射性质(AIEgen)的发光体在食品分析中显示出巨大的潜力,因为 AIEgen 可以有效地克服 ACQ 效应,具有更好的检测灵敏度、准确性和稳健性。在本综述中,我们回顾了 AIEgen 在食品安全监测方面的最新进展,重点介绍了 AIEgen 的分子设计和传感原理。强调了一些基于 AIE 的传感应用的例子,用于筛选食品污染物,并初步阐述了该新兴领域的未来展望和挑战。我们希望这篇综述能够激发新的研究思路和兴趣,帮助食品安全和质量控制,并促进更多的合作努力,推进先进的传感发展,缩小实验室研究和工业生产之间的实际转化差距。