Qiu Qin, Huang Yuge, Liu Xiaohua, Huang Fangfang, Li Xiaoling, Cui Liao, Luo Hui, Luo Lianxiang
Graduate School, Guangdong Medical University, Zhanjiang, China.
Department of Pediatrics, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Front Pharmacol. 2020 Nov 9;11:570893. doi: 10.3389/fphar.2020.570893. eCollection 2020.
The Coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 has been rapidly spreading globally and has caused worldwide social and economic disruption. Currently, no specific antiviral drugs or clinically effective vaccines are available to prevent and treat COVID-19. Traditional Chinese medicine (TCM) can facilitate syndrome differentiation and treatment according to the clinical manifestations of patients and has demonstrated effectiveness in epidemic prevention and control. In China, TCM intervention has helped to control the epidemic; however, TCM has not been fully recognized worldwide. In this review, we summarize the epidemiology and etiological characteristics of severe acute respiratory syndrome coronavirus 2 and the prevention and treatment measures of COVID-19. Additionally, we describe the application of TCM in the treatment of COVID-19 and the identification of small molecules of TCM that demonstrate anti-coronavirus activity. We also analyze the current problems associated with the recognition of TCM. We hope that, through the contribution of TCM, combined with modern technological research and the support of our international counterparts, COVID-19 can be effectively controlled and treated.
由严重急性呼吸综合征冠状病毒2引起的2019年冠状病毒病（COVID-19）大流行已在全球迅速蔓延，并造成了全球社会和经济混乱。目前，尚无用于预防和治疗COVID-19的特定抗病毒药物或临床有效的疫苗。中医可以根据患者的临床表现进行辨证论治，并已在疫情防控中显示出有效性。在中国，中医干预有助于控制疫情；然而，中医尚未在全球得到充分认可。在本综述中，我们总结了严重急性呼吸综合征冠状病毒2的流行病学和病因特征以及COVID-19的预防和治疗措施。此外，我们描述了中医在治疗COVID-19中的应用以及具有抗冠状病毒活性的中药小分子的鉴定。我们还分析了当前与中医认知相关的问题。我们希望，通过中医的贡献，结合现代技术研究和国际同行的支持，COVID-19能够得到有效控制和治疗。
