Cottrell J J
Department of Medicine, University of Illinois College of Medicine, Chicago.
Chest. 1988 Jan;93(1):81-4. doi: 10.1378/chest.93.1.81.
Commercial aircraft flight represents a highly variable altitude exposure that may result in significant hypoxemia for patients with cardiac or pulmonary disease. To develop better guidelines for travel by patients with cardiopulmonary disease, we measured inflight cabin altitude on 204 regularly scheduled commercial aircraft flights. Measurements were carried out on 16 different types of aircraft, operated by 28 airlines. The median altitude exposure for all flights was 6,214 feet (1894 m). Cabin altitudes ranged from sea level to 8,915 feet (2717 m). Inspired partial pressure of oxygen falls from 159 mm Hg at sea level to 127 mm Hg at 6,200 feet and further declines to 113 mm Hg at 9,000 ft. There was no significant difference between domestic and international flights. New generation aircraft fly at higher altitudes than older aircraft and are associated with greater altitude exposures to passengers (p = 0.002). The risk of hypoxemia may increase as newer model aircraft replace older ones.
商用飞机飞行意味着高度可变的海拔暴露，这可能会导致患有心脏或肺部疾病的患者出现明显的低氧血症。为了制定出针对心肺疾病患者旅行的更好指南，我们在204次定期商用飞机航班上测量了飞行中的机舱海拔。测量在由28家航空公司运营的16种不同型号的飞机上进行。所有航班的海拔暴露中位数为6214英尺（1894米）。机舱海拔范围从海平面到8915英尺（2717米）。吸入氧分压从海平面的159毫米汞柱下降到6200英尺处的127毫米汞柱，并在9000英尺处进一步降至113毫米汞柱。国内航班和国际航班之间没有显著差异。新一代飞机比旧飞机飞得更高，并且与乘客更高的海拔暴露相关（p = 0.002）。随着新型飞机取代旧飞机，低氧血症的风险可能会增加。
