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聚焦抗菌活性的组成与生物学特性

: Composition and Biological Properties with a Focus on Antimicrobial Activity.

作者信息

Rodrigues Márcio, Lopes Ana Clara, Vaz Filipa, Filipe Melanie, Alves Gilberto, Ribeiro Maximiano P, Coutinho Paula, Araujo André R T S

机构信息

School of Health Sciences, Polytechnic Institute of Guarda, Rua da Cadeia, 6300-035 Guarda, Portugal.

Research Unit for Inland Development (UDI), Polytechnic Institute of Guarda, Av. Dr. Francisco Sá Carneiro, 50, 6300-559 Guarda, Portugal.

出版信息

Pharmaceuticals (Basel). 2020 Dec 19;13(12):479. doi: 10.3390/ph13120479.

Abstract

has the appearance of a semishrub and can be found in jungles and rocky lands of the Iberian Peninsula. This work aimed to review and gather available scientific information on the composition and biological properties of . The main constituents of essential oil are 1,8-cineole (or eucalyptol) and linalool, while the extracts are characterized by the presence of flavonoids, phenolic acids, and terpenes. The essential oil and extracts of have demonstrated a wide diversity of biological activities. They showed antibacterial activity against several bacteria such as , , subsp., methicillin-resistant and methicillin-sensitive , , , and , among others, and antifungal activity against spp. and spp. Additionally, it has antioxidant activity, which has been evaluated through different methods. Furthermore, other activities have also been studied, such as anticancer, antiviral, insecticidal, repellent, anti-Alzheimer, and anti-inflammatory activity. In conclusion, considering the biological activities reported for the essential oil and extracts of , its potential as a preservative agent could be explored to be used in the food, cosmetic, or pharmaceutical industries.

摘要

呈半灌木状,生长于伊比利亚半岛的丛林和岩石地带。本研究旨在回顾和收集有关其成分及生物学特性的现有科学信息。其精油的主要成分是1,8-桉叶素(或桉油精)和芳樟醇,而提取物的特征在于含有黄酮类化合物、酚酸和萜类化合物。该植物的精油和提取物已展现出广泛多样的生物学活性。它们对多种细菌表现出抗菌活性,如[具体细菌名称1]、[具体细菌名称2]、[具体细菌名称3]亚种、耐甲氧西林和对甲氧西林敏感的[具体细菌名称4]、[具体细菌名称5]、[具体细菌名称6]和[具体细菌名称7]等,对[具体真菌名称1]属和[具体真菌名称2]属表现出抗真菌活性。此外,它具有抗氧化活性,已通过不同方法进行评估。再者,还研究了其他活性,如抗癌、抗病毒、杀虫、驱避、抗阿尔茨海默病和抗炎活性。总之,鉴于该植物精油和提取物所报道的生物学活性,可探索其作为防腐剂在食品、化妆品或制药行业中的潜在应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71a5/7766293/f63c52baaa39/pharmaceuticals-13-00479-g001.jpg

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