Onosakponome E O, Wogu M N
Department of Medical Laboratory Science, PAMO University of Medical Sciences, Port Harcourt, Nigeria.
Department of Animal and Environmental Biology, University of Port Harcourt, Nigeria.
J Parasitol Res. 2020 Dec 2;2020:8829848. doi: 10.1155/2020/8829848. eCollection 2020.
Data on the coinfection of malaria and COVID-19 is highly limited especially in Africa due to the novel nature of the pandemic COVID-19. Malaria and COVID-19 share striking similarities in their symptoms. A cross-sectional randomized study was conducted to investigate the role of sex in the coinfection of malaria and COVID-19 as well as some associated factors in Rivers State, Nigeria.
Ethical approval was obtained from the Rivers State Health and Ethics Committee before the commencement of this study, and the study was conducted at the COVID-19 Treatment Center Medical Laboratory, Rivers State, Nigeria. Intravenous blood samples from three hundred randomly selected consenting study participants were examined for species using Giemsa microscopy, while pretested questionnaires were used to obtain data on sex, risk factors, and symptoms. All data generated were analyzed statistically using the Chi-square test with a < 0.05 value considered significant.
All study participants had species (100% prevalence) with varying parasite loads, and . was the only species observed. Study participants (irrespective of sex) with low and high parasitaemia had the highest and least prevalence, respectively ( > 0.05). Male study participants experienced more symptoms than females ( > 0.05) except for sore throat which had an equal value among males and females. Travel history was the only risk factor that showed significant association with sex, and males had a higher value than females ( < 0.05).
Malaria and COVID-19 are major public health issues in Nigeria; more researches on these diseases especially in epidemiology, pathology, diagnosis, treatment, and vaccine production are vital.
由于新型冠状病毒肺炎(COVID-19)大流行的特殊性,疟疾与COVID-19合并感染的数据非常有限,尤其是在非洲。疟疾和COVID-19在症状上有显著相似之处。在尼日利亚河流州开展了一项横断面随机研究,以调查性别在疟疾与COVID-19合并感染中的作用以及一些相关因素。
在本研究开始前获得了河流州卫生与伦理委员会的伦理批准,研究在尼日利亚河流州COVID-19治疗中心医学实验室进行。使用吉姆萨显微镜对300名随机选择的同意参与研究的参与者的静脉血样本进行疟原虫种类检测,同时使用预先测试的问卷获取关于性别、危险因素和症状的数据。所有生成的数据均使用卡方检验进行统计分析,P<0.05被认为具有统计学意义。
所有研究参与者均感染疟原虫(感染率100%),寄生虫载量各不相同,且仅观察到间日疟原虫。疟原虫血症水平低和高的研究参与者(无论性别)分别具有最高和最低的感染率(P>0.05)。男性研究参与者比女性经历更多症状(P>0.05),但喉咙痛在男性和女性中的发生率相同。旅行史是唯一与性别有显著关联的危险因素,男性的发生率高于女性(P<0.05)。
疟疾和COVID-19是尼日利亚的主要公共卫生问题;对这些疾病尤其是在流行病学、病理学、诊断、治疗和疫苗生产方面进行更多研究至关重要。