KKF-Gesellschaft, Hans-Knöll-Str. 6, 07745 Jena, Germany.
KKF-Gesellschaft, Hans-Knöll-Str. 6, 07745 Jena, Germany; Experimental Rheumatology Unit, Department of Orthopedics, University Hospital Jena, Waldkliniken Eisenberg, Klosterlausnitzerstraße 81, 07607 Eisenberg, Germany.
Carbohydr Polym. 2021 Feb 15;254:117313. doi: 10.1016/j.carbpol.2020.117313. Epub 2020 Oct 30.
Biotech nanocellulose (bacterial nanocellulose, BNC) is a high potential natural polymer. Moreover, it is the only cellulose type that can be produced biotechnologically using microorganisms resulting in hydrogels with high purity, high mechanical strength and an interconnecting micropore system. Recently, the subject of intensive research is to influence this biosynthesis to create function-determining properties. This review reports on the progress in product design and today's state of technical and medical applications. A novel, dynamic, template-based technology, called Mobile Matrix Reservoir Technology (MMR Tech), is highlighted. Thereby, shape, dimensions, surface properties, and nanonetwork structures can be designed in a process-controlled manner. The formed multilayer materials open up new applications in medicine and technology. Especially medical materials for cardiovascular and visceral surgery, and drug delivery systems are developed. The effective production of layer-structured composites and coatings are important for potential applications in the electronics, paper, food and packaging technologies.
生物科技纳米纤维素（细菌纳米纤维素，BNC）是一种极具潜力的天然聚合物。此外，它是唯一可以通过微生物生物技术生产的纤维素类型，得到的水凝胶具有高纯度、高强度和互穿微孔系统。最近，人们对影响这种生物合成以创造功能决定性质的研究非常活跃。本文综述了在产品设计方面的进展以及当前技术和医学应用的状况。重点介绍了一种新颖的、动态的、基于模板的技术，称为移动基质储库技术（MMR Tech）。通过这种技术，可以以过程控制的方式设计形状、尺寸、表面性能和纳米网络结构。所形成的多层材料为医学和技术开辟了新的应用领域。特别是心血管和内脏手术的医学材料和药物输送系统得到了开发。层状复合材料和涂层的有效生产对于在电子、纸张、食品和包装技术中的潜在应用非常重要。
