Central Research Laboratory, Nigerian Institute of Medical Research, Yaba, Lagos.
Department of Biological Sciences, Redeemer's University, Ede, Osun state; African Centre of Excellence for Genomics of Infectious Diseases, Redeemer's University, Ede, Osun state.
J Natl Med Assoc. 2021 Jun;113(3):301-306. doi: 10.1016/j.jnma.2020.11.011. Epub 2020 Dec 24.
COVID-19 is an emerging, rapidly evolving global situation, infecting over 25 million people and causing more than 850,000 deaths. Several signs and symptoms have been described to be characteristic of the disease. However, there is a dearth of report on the description of the clinical characteristics of the disease in patients from Nigeria. This study was designed to provide a description of the clinical and demographic characteristics of COVID-19 patients in Nigeria.
This study is a case series that includes patients that are evaluated between May and August 2020, and diagnosed with COVID-19. Patient health records were reviewed and evaluated to describe the clinical characteristics on presentation.
A total of 154 COVID-19 patients were included in this study, with a mean age (S.D.) of 46.16 (13.701). Most of the patients survived (mortality rate of 2.6%), and were symptomatic (89.6%). There were more males (74.7%) than females, and the most common symptoms were fever, breathing difficulty, dry cough and malaise. Co-morbidities were also present in almost half of the study participants (49.4%).
This study presents the most extensive description, to date, on the clinical and demographic characteristics of COVID-19 patients in Nigeria. Males are more likely than females to be infected with COVID-19 and the most occurring symptoms are fever, breathing difficulty, malaise, dry cough and chest pain. Old age and the presence of co-morbidities may also be associated with developing the severe disease.
COVID-19 是一种新兴的、迅速发展的全球情况，已感染超过 2500 万人，并导致超过 85 万人死亡。已经描述了一些特征性的疾病症状和体征。然而，关于来自尼日利亚的 COVID-19 患者的疾病临床特征的描述报告却很少。本研究旨在提供尼日利亚 COVID-19 患者的临床和人口统计学特征描述。
这是一项病例系列研究，包括 2020 年 5 月至 8 月间评估并诊断为 COVID-19 的患者。回顾和评估患者的健康记录，以描述就诊时的临床特征。
本研究共纳入 154 例 COVID-19 患者，平均年龄（标准差）为 46.16（13.701）岁。大多数患者存活（死亡率为 2.6%）且有症状（89.6%）。男性多于女性（74.7%），最常见的症状是发热、呼吸困难、干咳和不适。近一半的研究参与者（49.4%）也存在合并症。
本研究迄今为止对尼日利亚 COVID-19 患者的临床和人口统计学特征进行了最广泛的描述。男性比女性更容易感染 COVID-19，最常见的症状是发热、呼吸困难、不适、干咳和胸痛。年龄较大和合并症的存在也可能与发生严重疾病有关。
