Zhang Xiu-Hang, Long Yu, Yu Qing-Hua, Cao Tianyi, Chen Xin-Xin, Yu Jia-Ao, Gao Xin-Xin
Department of Burn Surgery, The First Hospital of Jilin University, Changchun, China.
Department of Biological and Pharmaceutical Engineering, Wuhan, Hubei, China.
Mitochondrial DNA B Resour. 2019 Oct 24;4(2):3725-3726. doi: 10.1080/23802359.2019.1681319.
has a long history in medicine, which is one of the main export medicinal herb in China. The complete chloroplast genome of was assembled and reported in this study. The chloroplast genome was 161,541 bp in length as the circular and consisted a large single-copy (LSC) region of 86,519 bp, a small single-copy (SSC) region of 13,112 bp and a pair of inverted-repeat (IR) regions of 30,955 bp. The nucleotide composition was asymmetric 31.2% A (Adenine), 31.5% T (Thymine), 19.0% C (Cytosine), and 18.3% G (Guanine) with an overall G + C content of 37.3%. It encoded 131 genes, including 86 protein-coding genes (76 PCG species), 37 transfer RNA genes (26 tRNAs species), and eight ribosomal RNA genes (four rRNAs species). The Phylogenetic relationships used neighbour-joining (NJ) method and the result showed that and are phylogenetically related to each other in the family Polygonaceae. This study will be very important for Chinese medicinal herb research value and clinical drug development for future in China.
在医学上有着悠久的历史,是中国主要的出口药材之一。本研究组装并报道了其完整的叶绿体基因组。该叶绿体基因组呈环状,长度为161,541 bp,由一个86,519 bp的大单拷贝(LSC)区域、一个13,112 bp的小单拷贝(SSC)区域和一对30,955 bp的反向重复(IR)区域组成。核苷酸组成不对称,腺嘌呤(A)占31.2%,胸腺嘧啶(T)占31.5%,胞嘧啶(C)占19.0%,鸟嘌呤(G)占18.3%,总体G + C含量为37.3%。它编码131个基因,包括86个蛋白质编码基因(76种PCG)、37个转运RNA基因(26种tRNA)和8个核糖体RNA基因(4种rRNA)。系统发育关系采用邻接法(NJ),结果表明在蓼科中与彼此在系统发育上相关。本研究对中国未来的中药材研究价值和临床药物开发具有重要意义。