Pașca Claudia, Mărghitaș Liviu Alexandru, Dezmirean Daniel Severus, Matei Ioana Adriana, Bonta Victorița, Pașca Ioan, Chirilă Flore, Cîmpean Adrian, Iosif Fiț Nicodim
Department of Apiculture and Sericulture, Faculty of Animal Science and Biotechnologies, Cluj-Napoca, Romania.
Department of Microbiology Cluj-Napoca, Romania.
J Vet Res. 2020 Oct 20;64(4):523-529. doi: 10.2478/jvetres-2020-0067. eCollection 2020 Dec.
Bovine mastitis is an inflammatory disease of the udder that causes important economic losses in the animal breeding and dairy product industries. Nowadays, the conventional livestock antibiotic treatments are slowly being replaced by alternative treatments. In this context, the main aim of this study was to evaluate the efficacy of natural products in alternative treatment of bovine mastitis.
Two natural formulations with previously suggested antimicrobial effect were tested on mastitic cows. Animals with a positive diagnosis for mastitis (n = 20) were divided into three treatment groups: two groups (n = 8) were administered formulations of propolis, alcoholic extracts of Brewers Gold and Perle hops, plum lichen, common mallow, marigold, absinthe wormwood, black poplar buds, lemon balm, and essential oils of oregano, lavender, and rosemary designated R4 and R7 (differing only in the latter being more concentrated) and one group (n = 4) a conventional antibiotic mixture. efficacy of treatments was evaluated by somatic cell and standard plate counts, the treatment being considered efficacious when both parameters were under the maximum limit.
R7 was effective in the most cases, being therapeutically bactericidal in six out of eight cows, while R4 gave good results in three out of eight cows, and conventional antibiotics cured one out of four.
These results suggest the possible therapeutic potential of these natural products in bovine mastitis.
牛乳腺炎是一种乳腺的炎症性疾病，在动物养殖和乳制品行业造成重大经济损失。如今，传统的家畜抗生素治疗正逐渐被替代疗法所取代。在此背景下，本研究的主要目的是评估天然产物在牛乳腺炎替代治疗中的疗效。
对患有乳腺炎的奶牛测试了两种先前显示具有抗菌作用的天然制剂。乳腺炎诊断呈阳性的动物（n = 20）被分为三个治疗组：两组（n = 8）给予由蜂胶、布鲁尔金啤酒花和珍珠啤酒花的酒精提取物、李子地衣、锦葵、金盏花、苦艾、黑杨芽、柠檬香脂以及牛至、薰衣草和迷迭香精油组成的制剂，分别命名为R4和R7（仅后者浓度更高），另一组（n = 4）给予传统抗生素混合物。通过体细胞计数和标准平板计数评估治疗效果，当两个参数均低于最大限值时，该治疗被认为有效。
R7在大多数情况下有效，八头奶牛中有六头具有治疗杀菌作用，而R4在八头奶牛中有三头效果良好，传统抗生素在四头奶牛中治愈了一头。
这些结果表明这些天然产物在牛乳腺炎治疗中可能具有治疗潜力。
