Department of Pathology, Stanford University, Palo Alto, California, USA.
Division of HIV, Infectious Diseases, and Global Medicine, University of California, San Francisco, California, USA.
Clin Infect Dis. 2021 Nov 2;73(9):e3098-e3101. doi: 10.1093/cid/ciaa1890.
Among 3302 persons tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by BinaxNOWTM and reverse transcription polymerase chain reaction (RT-PCR) in a community setting, rapid assay sensitivity was 100%/98.5%/89% using RT-PCR cycle thresholds of 30, 35, and no threshold. The specificity was 99.9%. Performance was high across ages and those with and without symptoms. Rapid resulting permitted immediate public health action.
在社区环境中,使用 BinaxNOWTM 和逆转录聚合酶链反应(RT-PCR)对 3302 人进行了严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)检测,快速检测的灵敏度分别为 30、35 和无阈值 RT-PCR 循环阈值时为 100%/98.5%/89%。特异性为 99.9%。在各个年龄段以及有症状和无症状人群中的表现都很高。快速的结果可以立即采取公共卫生措施。