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一项肺癌病例对照研究中所报告的被动吸烟史的可靠性。

The reliability of passive smoking histories reported in a case-control study of lung cancer.

作者信息

Pron G E, Burch J D, Howe G R, Miller A B

机构信息

NCIC Epidemiology Unit, University of Toronto, Ontario, Canada.

出版信息

Am J Epidemiol. 1988 Feb;127(2):267-73. doi: 10.1093/oxfordjournals.aje.a114802.

DOI:10.1093/oxfordjournals.aje.a114802
PMID:3337082
Abstract

A test-retest design has been used to examine the reliability of passive smoking histories reported in personal interviews. A total of 117 control subjects initially interviewed in a lung cancer case-control study conducted in metropolitan Toronto, Canada, between 1983 and 1984 were reinterviewed on average six months later. Responses to initial screening questions used to detect a person's exposure to passive smoke were more reliable for residential than for occupational exposure. Respondents also more reliably reported residential exposure to spouse's passive smoke than to the passive smoke of others at home. Quantitative measures of exposure to passive smoke, i.e., number and duration of exposure, were even less reliably reported. Nonsmoking respondents gave the most reliable information. The low reliability of self-reported duration of exposure to passive smoke is consistent with the inability of several studies to detect a significant dose-response relation with lung cancer risk when measures of dose that depend solely on duration are used.

摘要

采用重测设计来检验在个人访谈中报告的被动吸烟史的可靠性。1983年至1984年期间,在加拿大多伦多市进行的一项肺癌病例对照研究中,最初接受访谈的117名对照受试者平均在六个月后再次接受访谈。用于检测一个人被动吸烟暴露情况的初始筛查问题的回答,对于家庭暴露而言比对职业暴露更可靠。与家中其他人的被动吸烟相比,受访者报告家庭中配偶的被动吸烟暴露情况也更可靠。被动吸烟暴露的定量测量,即暴露的次数和持续时间,报告的可靠性甚至更低。不吸烟的受访者提供了最可靠的信息。自我报告的被动吸烟暴露持续时间的低可靠性,与几项研究在仅使用依赖于持续时间的剂量测量方法时无法检测到与肺癌风险存在显著剂量反应关系的情况一致。

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