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深部蜂窝织炎:一项具有挑战性的诊断。

Deep neck cellulitis: a challenging diagnosis.

机构信息

Otorhinolaryngology, Pedro Hispano Hospital, Porto, Matosinhos, Portugal

Otorhinolaryngology, Pedro Hispano Hospital, Porto, Matosinhos, Portugal.

出版信息

BMJ Case Rep. 2020 Dec 18;13(12):e236415. doi: 10.1136/bcr-2020-236415.

DOI:10.1136/bcr-2020-236415
PMID:33370930
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7751200/
Abstract

A 38-year-old woman with Crohn's disease, under immunosuppressive therapy, was referred to the emergency department for severe progressive neck pain and fever, with 1 week of evolution. She was unable to perform neck mobilisation due to the intense pain aroused. She referred dysphagia. Oral cavity, oropharynx, hypopharynx and larynx showed no alterations. She had an increased C reactive protein. Central nervous system infections were excluded by lumbar puncture. CT was normal. Only MRI showed T2 hyperintensity of the retropharyngeal and prevertebral soft tissues of the neck without signs of abscess. The patient was treated with broad spectrum antibiotics. Complications of deep neck infection include abscess formation, venous thrombosis and mediastinitis. In this case, no complications occurred. A high degree of clinical suspicion is essential as deep neck infections need to be promptly diagnosed and treated given their rapidly progressive character, especially in immunocompromised patients.

摘要

一位 38 岁女性,患有克罗恩病,正在接受免疫抑制治疗,因严重进行性颈痛和发热,伴 1 周病程,被转至急诊。由于强烈的疼痛,她无法进行颈部活动。她诉吞咽困难。口腔、口咽、下咽和喉部未见异常。C 反应蛋白升高。腰椎穿刺排除中枢神经系统感染。CT 正常。只有 MRI 显示颈部咽后和椎前软组织的 T2 高信号,无脓肿迹象。患者接受了广谱抗生素治疗。深部颈感染的并发症包括脓肿形成、静脉血栓形成和纵隔炎。在本例中,未发生并发症。深部颈感染需要迅速诊断和治疗,因为其具有快速进展的特点,尤其是在免疫功能低下的患者中,因此高度的临床怀疑至关重要。

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本文引用的文献

1
Features of Prevertebral Disease in Patients Presenting to a Head and Neck Surgery Clinic with Neck Pain.因颈部疼痛前往头颈外科诊所就诊患者的椎前疾病特征。
Ann Maxillofac Surg. 2017 Jul-Dec;7(2):228-231. doi: 10.4103/ams.ams_54_17.
2
Deep neck infections: review of 263 cases.颈部深部感染:263例病例回顾
Otolaryngol Pol. 2017 Oct 30;71(5):37-42. doi: 10.5604/01.3001.0010.5315.
3
Deep neck cellulitis: limitations of conservative treatment with antibiotics.深部颈部蜂窝织炎:抗生素保守治疗的局限性
Acta Otolaryngol. 2017 Jan;137(1):86-89. doi: 10.1080/00016489.2016.1218048. Epub 2016 Aug 31.
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Prevention of infection caused by immunosuppressive drugs in gastroenterology.预防胃肠病学中免疫抑制药物引起的感染。
Ther Adv Chronic Dis. 2013 Jul;4(4):167-85. doi: 10.1177/2040622313485275.
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The long-term risk of continuous immunosuppression using thioguanides in inflammatory bowel disease.在炎症性肠病中使用硫唑嘌呤类药物进行长期免疫抑制的风险。
Ther Adv Chronic Dis. 2010 Jan;1(1):7-16. doi: 10.1177/2040622310368736.
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Clinical features of deep neck infections and predisposing factors for mediastinal extension.颈部深部感染的临床特征及纵隔扩展的易感因素。
Korean J Thorac Cardiovasc Surg. 2012 Jun;45(3):171-6. doi: 10.5090/kjtcs.2012.45.3.171. Epub 2012 Jun 7.
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Infections of the deep neck spaces.颈部深部间隙感染。
Singapore Med J. 2012 May;53(5):305-11; quiz 312.
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[Necrotizing fasciitis and cellulitis of the upper limb resulting from centipede bite: two case reports].[蜈蚣叮咬致上肢坏死性筋膜炎和蜂窝织炎:两例报告]
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Deep neck infection.颈部深部感染
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Predisposing factors of complicated deep neck infection: an analysis of 158 cases.复杂性颈部深部感染的易感因素:158例分析
Yonsei Med J. 2007 Feb 28;48(1):55-62. doi: 10.3349/ymj.2007.48.1.55.