Risner Derrick, Li Fangzhou, Fell Jason S, Pace Sara A, Siegel Justin B, Tagkopoulos Ilias, Spang Edward S
Department of Food Science and Technology, University of California, Davis, CA 95616, USA.
Department of Computer Science, University of California, Davis, CA 95616, USA.
Foods. 2020 Dec 22;10(1):3. doi: 10.3390/foods10010003.
Interest in animal cell-based meat (ACBM) or laboratory-grown meat has been increasing; however, the economic viability of these potential products has not been thoroughly vetted. Recent studies suggest monoclonal antibody production technology can be adapted for the industrialization of ACBM production. This study provides a scenario-based assessment of the projected cost per kilogram of ACBM produced in the United States based on cellular metabolic requirements and process/chemical engineering conventions. A sensitivity analysis of the model identified the nine most influential cost factors for ACBM production out of 67 initial parameters. The results indicate that technological performance will need to approach technical limits for ACBM to achieve profitably as a commodity. However, the model also suggests that low-volume high-value specialty products could be viable based on current technology.
对基于动物细胞的肉类（ACBM）或实验室培育肉类的兴趣一直在增加；然而，这些潜在产品的经济可行性尚未得到充分审查。最近的研究表明，单克隆抗体制备技术可适用于ACBM生产的工业化。本研究基于细胞代谢需求以及工艺/化学工程惯例，对美国生产的每千克ACBM的预计成本进行了基于情景的评估。对该模型的敏感性分析从67个初始参数中确定了ACBM生产的九个最具影响力的成本因素。结果表明，ACBM要作为一种商品实现盈利，其技术性能将需要接近技术极限。不过，该模型还表明，基于当前技术，小批量高价值的特色产品可能是可行的。
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