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欧洲中老年人肌少症、饮食、身体活动与肥胖:LifeAge 研究。

Sarcopenia, Diet, Physical Activity and Obesity in European Middle-Aged and Older Adults: The LifeAge Study.

机构信息

Research Group on Health, Physical Activity, Fitness and Motor Behaviour (GISAFFCOM) and Physical Activity and Sport Sciences Department, Faculty of Sport, Catholic University San Antonio of Murcia, 30107 Murcia, Spain.

Active Aging, Exercise and Health/HEALTHY-AGE Network, Consejo Superior de Deportes (CSD), Ministry of Culture and Sport of Spain, 28040 Madrid, Spain.

出版信息

Nutrients. 2020 Dec 22;13(1):8. doi: 10.3390/nu13010008.

Abstract

The revised European consensus defined sarcopenia as a progressive and generalized skeletal muscle disorder that is associated with an increased likelihood of adverse outcomes including falls, fractures, physical disability and mortality. The aim of this study was to determine the prevalence of sarcopenia and analyse the influence of diet, physical activity (PA) and obesity index as risk factors of each criteria of sarcopenia. A total of 629 European middle-aged and older adults were enrolled in this cross-sectional study. Anthropometrics were assessed. Self-reported PA and adherence to the Mediterranean diet were evaluated with the Global Physical Activity Questionnaire (GPAQ) and Prevention with Mediterranean Diet questionnaire (PREDIMED), respectively. The functional assessment included handgrip strength, lower body muscle strength, gait speed and agility/dynamic balance. Of the participants, 4.84% to 7.33% showed probable sarcopenia. Sarcopenia was confirmed in 1.16% to 2.93% of participants. Severe sarcopenia was shown by 0.86% to 1.49% of participants. Male; age group ≤65 years; lower body mass index (BMI); high levels of vigorous PA; and the consumption of more than one portion per day of red meat, hamburgers, sausages or cold cuts and/or preferential consumption of rabbit, chicken or turkey instead of beef, pork, hamburgers or sausages (OR = 0.126-0.454; all < 0.013) resulted as protective factors, and more time of sedentary time (OR = 1.608-2.368; = 0.032-0.041) resulted as a risk factor for some criteria of sarcopenia. In conclusion, age, diet, PA, and obesity can affect the risk of having low muscle strength, low muscle mass or low functional performance, factors connected with sarcopenia.

摘要

欧洲共识修订版将肌肉减少症定义为一种进行性和全身性的骨骼肌疾病,与不良后果(包括跌倒、骨折、身体残疾和死亡)的发生几率增加相关。本研究旨在确定肌肉减少症的患病率,并分析饮食、身体活动(PA)和肥胖指数作为肌肉减少症各标准风险因素的影响。共有 629 名欧洲中老年人参与了这项横断面研究。评估了人体测量学指标。使用全球体力活动问卷(GPAQ)和地中海饮食预防问卷(PREDIMED)分别评估自我报告的 PA 和对地中海饮食的依从性。功能评估包括握力、下肢肌肉力量、步态速度和敏捷性/动态平衡。参与者中,4.84%至 7.33%可能存在肌肉减少症。1.16%至 2.93%的参与者被确诊为肌肉减少症。0.86%至 1.49%的参与者出现严重肌肉减少症。男性;年龄组≤65 岁;下肢 BMI;高强度 PA;每天食用超过一份的红肉、汉堡、香肠或冷切肉,或优先食用兔子、鸡肉或火鸡代替牛肉、猪肉、汉堡或香肠(OR=0.126-0.454;均<0.013)是保护因素,而久坐时间(OR=1.608-2.368;<0.032-0.041)是某些肌肉减少症标准的风险因素。总之,年龄、饮食、PA 和肥胖会影响低肌肉力量、低肌肉质量或低功能表现的风险因素,这些因素与肌肉减少症有关。

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