Akpa Onoja Matthew, Okekunle Akinkunmi Paul, Asowata Jeffery Osahon, Adedokun Babatunde
Department of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, PMB 900001 UI Post Office, Ibadan, 200284, Nigeria.
Center for Genomic and Precision Medicine, College of Medicine, University of Ibadan, Ibadan, 200284, Nigeria.
Clin Hypertens. 2021 Jan 1;27(1):1. doi: 10.1186/s40885-020-00159-7.
Hypertension is a major public health problem and a prominent risk factor for cardiovascular diseases. However, whether passive smoking exposure (PSE) is associated with the risk of hypertension is scarcely understood. This study assessed the association between PSE and the risk of hypertension among adults (≥18 years) in the United States of America.
Three thousand and sixty-seven adults were identified from the 2015-2016 National Health and Nutrition Examination Survey and the association between PSE and hypertension (adjusting for relevant confounders) was examined using multivariable adjusted-logistic regression analysis at P < 0.05.
Mean age of respondents was 46.5 ± 17.9 years. Overall, 23.7% of respondents reported PSE and 32.6% were hypertensives (of which only 14.3% were aware of their hypertensive state) Also, adjusted odds of hypertension for participants with PSE was 1.038 (1.037, 1.040), P < 0.0001, in the overall population. Also, PSE aggravated odds of hypertension among young adults - < 60 years (aOR: 1.095, 95CI%: 1.094 to 1.097), P < 0.0001, and old adults - ≥60 years (aOR: 1.110, 95% CI: 1.108 to 1.113), P < 0.0001. Similarly, PSE was associated with increased odds of hypertension among women (aOR: 1.240, 95% CI: 1.238 to 1.242), P < 0.0001 but not among men (aOR: 0.755, 95% CI: 0.754 to 0.757), P < 0.0001.
PSE was independently associated with the risk of hypertension particularly among women, young and old adults. A multi-ethnic longitudinal cohort may help ascertain causality and provide more evidence for appropriate interventions.
高血压是一个主要的公共卫生问题,也是心血管疾病的一个突出危险因素。然而,被动吸烟暴露(PSE)是否与高血压风险相关却鲜为人知。本研究评估了美国成年人(≥18岁)中PSE与高血压风险之间的关联。
从2015 - 2016年国家健康与营养检查调查中识别出3067名成年人,并使用多变量调整逻辑回归分析在P < 0.05的水平下检验PSE与高血压之间的关联(对相关混杂因素进行调整)。
受访者的平均年龄为46.5 ± 17.9岁。总体而言,23.7%的受访者报告有PSE,32.6%为高血压患者(其中只有14.3%意识到自己的高血压状态)。此外,在总体人群中,有PSE的参与者患高血压的调整后比值比为1.038(1.037,1.040),P < 0.0001。同样,PSE增加了60岁以下年轻人患高血压的几率(调整后比值比:1.095,95%置信区间:1.094至1.097),P < 0.0001,以及60岁及以上老年人患高血压的几率(调整后比值比:1.110,95%置信区间:1.108至1.113),P < 0.0001。同样,PSE与女性患高血压几率增加相关(调整后比值比:1.240,95%置信区间:1.238至1.242),P < 0.0001,但与男性无关(调整后比值比:0.755,95%置信区间:0.754至0.757),P < 0.0001。
PSE与高血压风险独立相关,尤其是在女性、年轻人和老年人中。一个多民族纵向队列可能有助于确定因果关系,并为适当的干预措施提供更多证据。