Valletta E A, Bonazzi L, Zuanazzi R, Del Col G, Andreoli A, Stocchero L, Boner A L
Clinica Pediatrica, Universitá di Verona, Italy.
Eur J Pediatr. 1988 Jan;147(1):68-70. doi: 10.1007/BF00442615.
Plasma fibronectin (FN) concentrations were measured by an immunonephelometric method in cord blood from 76 healthy newborns (45 full term and 31 preterm), in 181 healthy children, from 1 month-15 years old, divided by age into seven groups and in 81 control adults. FN levels in newborns were 35% of those of adults. There was no difference between plasma FN in term and preterm (gestational age greater than 30 weeks) infants. Preterm newborns below the gestational age of 30 weeks showed particularly low FN levels. No clear correlation was seen with birth weight. In the child population, a strong increase in FN values was noted in the first 6 months of life, rising to 65% of the normal adult values. No further increase occurred until puberty.
采用免疫比浊法测定了76例健康新生儿（45例足月儿和31例早产儿）、181例1个月至15岁的健康儿童（按年龄分为7组）以及81例对照成人的脐血中血浆纤维连接蛋白（FN）浓度。新生儿的FN水平为成人的35%。足月儿和早产儿（胎龄大于30周）的血浆FN无差异。胎龄低于30周的早产儿FN水平特别低。未发现与出生体重有明显相关性。在儿童群体中，出生后头6个月FN值显著升高，升至正常成人值的65%。青春期前无进一步升高。
