I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.
Pol Merkur Lekarski. 2020 Dec 22;48(288):422-426.
Medical sponge is a tool that has absorbent and antiseptic properties, as well as stimulates tissue regeneration and is used in surgery, neurosurgery, dentistry, otolaryngology and gynecology to stop blood loss or to close wound surfaces (burns, trophic ulcers). To summarize the information of the professional literature on medical (hemostatic) sponges, their classification and applications, the areas of their use in medical practice and also modern excipients and active pharmaceutical ingredients that can be used in their technology.
The aim of the study was to summarize data on the characteristics, classification of medical sponges, auxiliary substances and active pharmaceutical ingredients used in the technology of these agents and medical use.
Methods of information retrieval, analysis of statistics and scientific literature on medical sponges and prospects of their use were applied in the study.
Despite the creation and research of a large number of medical sponges based on gelatin, chitosan, cellulose derivatives, collagen and other excipients, as well as the clinical demonstration of their efficacy and need for use, medical sponges are still need refinement and further study. Because of it, the search for the perfect foundation to create universal medical sponge is still ongoing.
Expanding the range of medical sponges and researching new excipients for their manufacture are a promising area of modern medicine and pharmacy.
医用海绵是一种具有吸水性和抗菌性的工具，可刺激组织再生，用于外科、神经外科、牙科、耳鼻喉科和妇产科，以止血或封闭创面（烧伤、营养性溃疡）。总结医用（止血）海绵的专业文献信息，其分类和应用，在医学实践中的使用领域，以及可用于其技术的现代辅料和活性药物成分。
本研究旨在总结医用海绵的特性、分类、辅料和活性药物成分在这些制剂和医疗用途中的技术应用数据。
在研究中应用了信息检索方法、对医用海绵及其使用前景的统计和科学文献分析。
尽管基于明胶、壳聚糖、纤维素衍生物、胶原和其他辅料，以及临床证明其疗效和使用必要性，创造了大量的医用海绵，但医用海绵仍需要改进和进一步研究。因此，寻找创造通用医用海绵的完美基础仍在进行中。
扩大医用海绵的范围并研究其制造的新辅料是现代医学和药学的一个有前途的领域。
