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呼气分析在疾病检测中的应用。

Exhaled breath analysis in disease detection.

机构信息

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, PR China.

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, PR China.

出版信息

Clin Chim Acta. 2021 Apr;515:61-72. doi: 10.1016/j.cca.2020.12.036. Epub 2020 Dec 31.

Abstract

Investigating the use of exhaled breath analysis to diagnose and monitor different diseases has attracted much interest in recent years. This review introduces conventionally used methods and some emerging technologies aimed at breath analysis and their relevance to lung disease, airway inflammation, gastrointestinal disorders, metabolic disorders and kidney diseases. One section correlates breath components and specific diseases, whereas the other discusses some unique ideas, strategies, and devices to analyze exhaled breath for the diagnosis of some common diseases. This review aims to briefly introduce the potential application of exhaled breath analysis for the diagnosis and screening of various diseases, thereby providing a new avenue for the detection of non-invasive diseases.

摘要

近年来,利用呼气分析来诊断和监测各种疾病引起了广泛关注。本综述介绍了常用于呼气分析的方法和一些新兴技术,及其与肺部疾病、气道炎症、胃肠道疾病、代谢紊乱和肾脏疾病的相关性。一部分内容是关于呼气成分与特定疾病的相关性,另一部分则讨论了一些用于分析呼气以诊断某些常见疾病的独特思路、策略和设备。本综述旨在简要介绍呼气分析在各种疾病诊断和筛查中的潜在应用,从而为非侵入性疾病的检测提供新途径。

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