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呼气分析在疾病检测中的应用。

Exhaled breath analysis in disease detection.

机构信息

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, PR China.

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, PR China.

出版信息

Clin Chim Acta. 2021 Apr;515:61-72. doi: 10.1016/j.cca.2020.12.036. Epub 2020 Dec 31.

DOI:10.1016/j.cca.2020.12.036
PMID:33387463
Abstract

Investigating the use of exhaled breath analysis to diagnose and monitor different diseases has attracted much interest in recent years. This review introduces conventionally used methods and some emerging technologies aimed at breath analysis and their relevance to lung disease, airway inflammation, gastrointestinal disorders, metabolic disorders and kidney diseases. One section correlates breath components and specific diseases, whereas the other discusses some unique ideas, strategies, and devices to analyze exhaled breath for the diagnosis of some common diseases. This review aims to briefly introduce the potential application of exhaled breath analysis for the diagnosis and screening of various diseases, thereby providing a new avenue for the detection of non-invasive diseases.

摘要

近年来,利用呼气分析来诊断和监测各种疾病引起了广泛关注。本综述介绍了常用于呼气分析的方法和一些新兴技术,及其与肺部疾病、气道炎症、胃肠道疾病、代谢紊乱和肾脏疾病的相关性。一部分内容是关于呼气成分与特定疾病的相关性,另一部分则讨论了一些用于分析呼气以诊断某些常见疾病的独特思路、策略和设备。本综述旨在简要介绍呼气分析在各种疾病诊断和筛查中的潜在应用,从而为非侵入性疾病的检测提供新途径。

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1
Exhaled breath analysis in disease detection.呼气分析在疾病检测中的应用。
Clin Chim Acta. 2021 Apr;515:61-72. doi: 10.1016/j.cca.2020.12.036. Epub 2020 Dec 31.
2
Recent Trends in Exhaled Breath Diagnosis Using an Artificial Olfactory System.人工嗅觉系统在呼气诊断中的最新研究进展。
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Sensors for detecting pulmonary diseases from exhaled breath.用于从呼气中检测肺部疾病的传感器。
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News from the Breath Analysis Summit 2011.2011年呼吸分析峰会新闻。
J Breath Res. 2012 Jun;6(2):020201. doi: 10.1088/1752-7155/6/2/020201. Epub 2012 May 23.
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Exhaled breath condensate: determination of non-volatile compounds and their potential for clinical diagnosis and monitoring. A review.呼出气冷凝物:非挥发性化合物的测定及其在临床诊断和监测中的潜在应用。综述。
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Detection of volatile organic compounds (VOCs) from exhaled breath as noninvasive methods for cancer diagnosis.检测呼出气体中的挥发性有机化合物(VOCs)作为癌症诊断的非侵入性方法。
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Biomarkers of some pulmonary diseases in exhaled breath.呼出气体中某些肺部疾病的生物标志物。
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Exhaled breath analysis: from occupational to respiratory medicine.呼气分析:从职业医学到呼吸医学
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Non-volatile compounds in exhaled breath condensate: review of methodological aspects.呼出气冷凝物中的非挥发性化合物:方法学方面的综述。
Anal Bioanal Chem. 2018 Oct;410(25):6411-6440. doi: 10.1007/s00216-018-1259-4. Epub 2018 Jul 25.
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