Department of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha, Qatar.
Biomedical Research Center, Qatar University, Doha, Qatar.
Arch Virol. 2021 Feb;166(2):335-345. doi: 10.1007/s00705-020-04891-1. Epub 2021 Jan 3.
Meningitis is a serious condition that affects the central nervous system. It is an inflammation of the meninges, which is the membrane that surrounds both the brain and the spinal cord. Meningitis can be caused by bacterial, viral, or fungal infections. Many viruses, such as enteroviruses, herpesviruses, and influenza viruses, can cause this neurological disorder. However, enteroviruses have been found to be the underlying cause of most viral meningitis cases worldwide. With few exceptions, the clinical manifestations and symptoms associated with viral meningitis are similar for the different causative agents, which makes it difficult to diagnose the disease at early stages. The pathogenesis of viral meningitis is not clearly defined, and more studies are needed to improve the health care of patients in terms of early diagnosis and management. This review article discusses the most common causative agents, epidemiology, clinical features, diagnosis, and pathogenesis of viral meningitis.
脑膜炎是一种影响中枢神经系统的严重疾病。它是脑膜的炎症，脑膜是包围大脑和脊髓的膜。脑膜炎可由细菌、病毒或真菌感染引起。许多病毒，如肠道病毒、疱疹病毒和流感病毒，都可引起这种神经系统疾病。然而，肠道病毒已被发现是全球大多数病毒性脑膜炎病例的根本原因。除了少数例外，与病毒性脑膜炎相关的临床表现和症状在不同的病原体中是相似的，这使得在早期阶段诊断这种疾病变得困难。病毒性脑膜炎的发病机制尚不清楚，需要更多的研究来改善患者的医疗保健，包括早期诊断和管理。这篇综述文章讨论了病毒性脑膜炎最常见的病原体、流行病学、临床特征、诊断和发病机制。
