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巴基斯坦药品道德推广的认知与障碍:医药代表和医生的观点

Perceptions of and barriers to ethical promotion of pharmaceuticals in Pakistan: perspectives of medical representatives and doctors.

作者信息

Gul Rehan, Saeed Hamid, Saleem Zikria, Rasool Fawad, Hashmi Furqan Kurshid, Islam Muhammad, Imran Imran, Raza Syed Atif, Danish Zeeshan

机构信息

College of Pharmacy, Universality of the Punjab, Allama Iqbal Campus, Lahore, 54000, Pakistan.

Department of Pharmacy, University of Lahore, Lahore, Pakistan.

出版信息

BMC Med Ethics. 2021 Jan 4;22(1):2. doi: 10.1186/s12910-020-00569-0.

Abstract

BACKGROUND

In Pakistan, drug promotion practices, ethical or unethical, have rarely been in the spotlight. We aimed to assess the perception and barriers of medical representatives (MRs) and doctors (MDs) regarding ethical promotion of pharmaceuticals in Pakistan.

METHODS

A cross sectional survey was conducted in seven major cities of Pakistan for 6-months period. Self-administered questionnaire was used for data collection. Logistic regression and five-point Likert scale scoring was used to estimate the perceptions and barriers.

RESULTS

Compared to national companies (NCs), the medical representatives (MRs) of multinational companies (MNCs) strongly believed that their companies follow World Health Organization (WHO) (OR; 5.31, p = 0.0005), International Federation of Pharmaceutical Manufacturers & Associations (IFPMA) (OR; 6.45, p = 0.0005) and national codes of ethics (OR; 5.84, p = 0.0005). MNCs trained their MRs (OR; 6.68, p = 0.0005), provide accurate and valid scientific data (OR; 4.01, p = 0.007) with adequate system of accountability and controls on product samples (OR; 1.96, p = 0.047), while, NCs sponsor social or entertainment activities, seminars and conferences, and all sort of facilitation in form of gifts of their choice and clinic renovation for medical doctors (MDs). MDs perceptions were similar to MRs mentioned above, yet strongly agreed that companies offer cash payments or equivalents to MDs. The MRs of NCs/MNCs and MDs agreed/strongly agreed that no external accountability, profiteering, pressure on sale targets, job insecurity, condoning unethical promotion by high-ups' and business promotion by junior MDs were the predominant barriers.

CONCLUSION

In conclusion, MRs of MNCs and MDs believed that MNCs follow certain codes of ethics in the promotion of pharmaceuticals, while NCs tend to be more profit oriented and even condone unethical promotion. All stakeholders, MRs, MDs and companies, might pose certain barriers, intentionally or unintentionally, in ethical promotion.

摘要

背景

在巴基斯坦,药品促销行为,无论合乎道德与否,很少受到关注。我们旨在评估巴基斯坦医药代表(MRs)和医生(MDs)对药品道德促销的认知及障碍。

方法

在巴基斯坦七个主要城市进行了为期6个月的横断面调查。采用自填式问卷收集数据。运用逻辑回归和五点李克特量表评分来评估认知和障碍。

结果

与国内公司(NCs)相比,跨国公司(MNCs)的医药代表坚信其公司遵循世界卫生组织(WHO)(比值比[OR];5.31,p = 0.0005)、国际制药商协会联合会(IFPMA)(OR;6.45,p = 0.0005)以及国家道德规范(OR;5.84,p = 0.0005)。跨国公司培训其医药代表(OR;6.68,p = 0.0005),提供准确有效的科学数据(OR;4.01,p = 0.007),并对产品样本建立了完善的问责和控制系统(OR;1.96,p = 0.047),而国内公司则赞助社交或娱乐活动、研讨会和会议,并以他们选择的礼品形式以及为医生翻新诊所等各种便利措施来进行促销。医生的认知与上述医药代表相似,但他们强烈认同公司会向医生提供现金支付或等价物。国内公司/跨国公司的医药代表和医生一致/强烈认同,缺乏外部问责、暴利、销售目标压力、工作不安全感、高层对不道德促销的纵容以及初级医生进行商业促销是主要障碍。

结论

总之,跨国公司的医药代表和医生认为跨国公司在药品促销方面遵循某些道德规范,而国内公司则更倾向于以盈利为导向,甚至纵容不道德促销。所有利益相关者,包括医药代表、医生和公司,可能有意或无意地在道德促销方面设置某些障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa38/7783997/8f4f42a0f45a/12910_2020_569_Fig1_HTML.jpg

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