Dr Rajendra Prasad Centre for Ophthalmic Sciences.
Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.
J Glaucoma. 2021 Apr 1;30(4):312-316. doi: 10.1097/IJG.0000000000001765.
Icare tonometer overestimated intraocular pressure (IOP) as compared with Perkins and this variation was higher in IOP>19 mm Hg and corneal opacity in patients with pediatric glaucoma.
To compare the IOP measured by Icare ic200 with Perkins tonometer in pediatric glaucoma with different corneal characteristics.
Patients of pediatric glaucoma posted for routine examination under anesthesia, age below 12 years were enrolled. All patients underwent IOP measurement with Perkins and Icare ic200 tonometer by the same observer. Basic demographic data and other relevant clinical data were recorded. Central corneal thickness (CCT), horizontal corneal diameter, and corneal characteristics such as cornea clarity was recorded.
A total of 194 eyes of 105 patients were analyzed. The difference between Perkins and Icare IOP was -0.816 mm Hg with the Bland-Altman plot 95% limits of agreement (LoA) from -11.194 to 9.562 mm Hg and 5.1% (10) values lying outside LoA. At IOP <19 mm Hg, the difference was -0.65 mm Hg and IOP ≥19 mm Hg, the difference was higher, -1.12 mm Hg. In the clear cornea group (123 eyes), the difference in IOP by 2 tonometers was -0.776 mm Hg with the Bland-Altman plot 95% LoA between -10.679 and 9.128 mm Hg. In hazy corneas (36 eyes), the difference in IOP was 0.531 mm Hg. The Bland-Altman plot showed 95% LoA between -6.242 and 7.303 mm Hg. In the scarred cornea group (35 eyes), the difference in IOP between the 2 was -2.343 mm Hg and the Bland-Altman plot showed wide 95% LoA from -16.302 to 11.616 mm Hg.
Icare tonometer overestimated IOP as compared with Perkins and this variation was higher in eyes with IOP≥19 mm Hg, CCT >615 μm, and scarred corneas. A moderate correlation between IOP and CCT for both tonometers was noted.
与 Perkins 眼压计相比，Icare 眼压计高估了眼压（IOP），并且在 IOP>19mmHg 和角膜混浊的儿童青光眼患者中，这种差异更高。
比较不同角膜特征的儿童青光眼患者中 Icare ic200 眼压计与 Perkins 眼压计测量的 IOP。
对全麻下接受常规检查的儿童青光眼患者（年龄<12 岁）进行研究。由同一位观察者使用 Perkins 和 Icare ic200 眼压计测量所有患者的 IOP。记录基本人口统计学数据和其他相关临床数据。记录中央角膜厚度（CCT）、水平角膜直径以及角膜清晰度等角膜特征。
共分析了 105 例患者的 194 只眼。Perkins 和 Icare IOP 之间的差值为-0.816mmHg，Bland-Altman 图 95%一致性界限（LoA）为-11.194 至 9.562mmHg，5.1%（10）个值超出 LoA。在 IOP<19mmHg 时，差值为-0.65mmHg，IOP≥19mmHg 时，差值更高，为-1.12mmHg。在透明角膜组（123 只眼）中，2 种眼压计测量的 IOP 差值为-0.776mmHg，Bland-Altman 图 95%LoA 为-10.679 至 9.128mmHg。在混浊角膜组（36 只眼）中，IOP 差值为 0.531mmHg。Bland-Altman 图显示 95%LoA 为-6.242 至 7.303mmHg。在瘢痕角膜组（35 只眼）中，2 种眼压计测量的 IOP 差值为-2.343mmHg，Bland-Altman 图显示 95%LoA 很宽，为-16.302 至 11.616mmHg。
与 Perkins 眼压计相比，Icare 眼压计高估了 IOP，并且在 IOP≥19mmHg、CCT>615μm 和瘢痕性角膜的患者中，这种差异更大。两种眼压计的 IOP 与 CCT 之间存在中度相关性。
