Co-Infection with Species and Novel Genetic Variants Detected in Cattle and Goats in the Republic of Korea.

Anaplasmosis, a tick-borne disease with multiple reservoirs, has been evolving in its pathogenesis, increasing domestic ruminants susceptibility to simultaneous infections with multiple pathogens. However, there is limited information regarding anaplasmosis in domestic ruminants in the Republic of Korea (ROK). We aimed to evaluate the role of Korean cattle and goats in infection maintenance. Polymerase chain reaction was performed to investigate the prevalence and genetic diversity of spp. from 686 whole blood samples collected from different ROK provinces. infection was mostly caused by (21.1%) in cattle, and (7.3%) in goats. Co-infection cases were found in cattle: and (16.7%), and in goats: and (1.0%). Notably, a triple co-infection with , , and was found in one cow. Phylogenetic analysis revealed novel variants of the and genes. This research contributes to the ratification of cattle as a potential reservoir of and demonstrates co-infection types in Korean domestic ruminants. As anaplasmosis is a zoonotic disease, our study could be crucial in making important decisions for public health.