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皮肤之外——一例罕见的原发性肺黑色素瘤合并支气管内曲霉菌瘤病例

Beyond the skin - A rare case of primary pulmonary melanoma and endobronchial aspergilloma.

作者信息

Silvestre Carina Rôlo, Cavaco Maria, Nunes André, Cordeiro Ricardo José, Torres Carolina, Ribeiro Analisa, André Natália, Falcão Teresa, Félix Francisco, Domingos António Carlos

机构信息

Pulmonology Department - Centro Hospitalar do Oeste, Rua Dr. Aurélio Ricardo Belo, 2560-364, Torres Vedras, Portugal.

Thoracic Surgery Department - Hospital Pulido Valente, Centro Hospitalar Lisboa Norte, Alameda das Linhas de Torres 117, 1769-001, Lisboa, Portugal.

出版信息

Respir Med Case Rep. 2022 Feb 19;36:101605. doi: 10.1016/j.rmcr.2022.101605. eCollection 2022.

Abstract

Melanoma is an aggressive skin tumor, but it may be present in other locations. Primary lung melanoma and endobronchial aspergilloma are rare entities. The authors report a case of a 72-year-old, asthmatic woman, with worsening of her respiratory complaints. Imaging revealed finger in glove sign at the left hemithorax. Bronchoscopy revealed an elongated mass with evidence of Despite endoscopic mass removal, the patient maintained the nodular imaging at the left hemithorax. She underwent thoracic surgery, and the histological evaluation identified malignant melanoma. After undergoing a thorough evaluation, we excluded other melanocytic lesions, and assumed the diagnosis of primary malignant lung melanoma. This case demonstrates a rare association between endobronchial aspergilloma and primary lung melanoma, raising awareness of considering the co-existence of lung tumor in the presence of endobronchial aspergilloma, and showing endobronchial aspergilloma mimicking malignant lesions.

摘要

黑色素瘤是一种侵袭性皮肤肿瘤,但也可能出现在其他部位。原发性肺黑色素瘤和支气管内曲霉菌瘤是罕见的病症。作者报告了一例72岁的哮喘女性病例,其呼吸道症状加重。影像学检查显示左半胸出现手套征。支气管镜检查发现一个细长肿块,有……的证据。尽管通过内镜切除了肿块,但患者左半胸的结节状影像仍持续存在。她接受了胸外科手术,组织学评估确诊为恶性黑色素瘤。经过全面评估,我们排除了其他黑素细胞病变,诊断为原发性恶性肺黑色素瘤。该病例显示了支气管内曲霉菌瘤与原发性肺黑色素瘤之间罕见的关联,提高了在支气管内曲霉菌瘤存在时考虑肺部肿瘤并存的意识,并表明支气管内曲霉菌瘤可模仿恶性病变。 (原文中“with evidence of”后面内容缺失)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9757/8866094/ae5e847146b1/gr1a.jpg

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