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中国北京不同医院级别心力衰竭住院患者的医疗质量与死亡率

Healthcare quality and mortality among patients hospitalized for heart failure by hospital level in Beijing, China.

作者信息

He Liu, Dong Zhao-Jie, Du Xin, Jiang Chao, Chen Ning, Xia Shi-Jun, Hou Xiao-Xia, Yu Hai-Rong, Lv Qiang, Yu Rong-Hui, Long De-Yong, Bai Rong, Liu Nian, Sang Cai-Hua, Jiang Chen-Xi, Li Song-Nan, Huffman Mark D, Dong Jian-Zeng, Ma Chang-Sheng

机构信息

Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases, Beijing Advanced Innovation Center for Big Data-Based Precision Medicine for Cardiovascular Diseases, No. 2, Anzhen Road, Chaoyang District, Beijing, 100029, China.

Heart Health Research Center, Beijing, China.

出版信息

ESC Heart Fail. 2021 Apr;8(2):1186-1194. doi: 10.1002/ehf2.13178. Epub 2021 Jan 5.

Abstract

AIMS

This study sought to compare healthcare quality and 30 day, 90 day, and 1 year mortality rates among patients admitted to secondary and tertiary hospitals for heart failure (HF) in Beijing.

METHODS AND RESULTS

This study retrospectively enrolled patients hospitalized with a primary discharge diagnosis of HF during January 2014 to December 2015, from five tertiary and four secondary hospitals, in Beijing, China. Mortality data were extracted from Beijing Death Surveillance Database. HF healthcare quality indices were used to evaluate in-hospital care. Associations between hospital level and mortality rates were assessed using generalized linear mixed models, adjusting for patients' baseline characteristics and intra-hospital correlation. Data from 1413 patients (median [interquartile range] age = 74 [65-80] years, 52.7% female) from secondary hospitals and 1250 patients (median [interquartile range] age = 72 [61-79] years, 43.3% female) from tertiary hospitals were collected. Rates of left ventricular ejection fraction assessment (73.2% vs. 90.1%) and combined use of β-blockers and angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers (30.1% vs. 49.3%) were lower in secondary hospitals than those in tertiary hospitals, respectively. Patients admitted to secondary hospitals had a higher 90 day mortality [10.8% vs. 5.0%; adjusted odds ratio (OR): 2.06; 95% confidence interval (CI): 1.10-3.84, P = 0.024 and a higher 1 year mortality rate [21.0% vs. 12.1%; adjusted OR: 1.64; 95% CI: 1.02-2.62, P = 0.039], but 30 day mortality rates were not significantly different (5.5% vs. 3.0%; adjusted OR: 1.49; 95% CI: 0.63-3.52, P = 0.368).

CONCLUSIONS

Worse quality of care for patients with HF in secondary hospitals was associated with higher 90 day and 1 year mortality rates. Improving care quality in secondary hospitals is crucial to improve prognosis of patients they served.

摘要

目的

本研究旨在比较北京二级和三级医院收治的心力衰竭(HF)患者的医疗质量以及30天、90天和1年死亡率。

方法与结果

本研究回顾性纳入了2014年1月至2015年12月期间在中国北京的五家三级医院和四家二级医院住院治疗且主要出院诊断为HF的患者。死亡率数据从北京死亡监测数据库中提取。使用HF医疗质量指标评估住院治疗情况。采用广义线性混合模型评估医院级别与死亡率之间的关联,并对患者的基线特征和医院内相关性进行校正。收集了来自二级医院的1413例患者(年龄中位数[四分位间距]=74[65 - 80]岁,女性占52.7%)和来自三级医院的1250例患者(年龄中位数[四分位间距]=72[61 - 79]岁,女性占43.3%)的数据。二级医院的左心室射血分数评估率(73.2%对90.1%)和β受体阻滞剂与血管紧张素转换酶抑制剂/血管紧张素II受体阻滞剂联合使用率(30.1%对49.3%)分别低于三级医院。二级医院收治的患者90天死亡率较高[10.8%对5.0%;校正优势比(OR):2.06;95%置信区间(CI):1.10 - 3.84,P = 0.024],1年死亡率也较高[21.0%对12.1%;校正OR:1.64;95% CI:1.02 - 2.62,P = 0.039],但30天死亡率无显著差异(5.5%对3.0%;校正OR:1.49;95% CI:0.63 - 3.52,P = 0.368)。

结论

二级医院中HF患者的护理质量较差与90天和1年死亡率较高相关。提高二级医院的护理质量对于改善其所服务患者的预后至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/043d/8006727/bb7d1c1a42f8/EHF2-8-1186-g001.jpg

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