Wei Fang, Xue Panqi, Fang Xinglin, Lou Xiaoming, Sun Jingyi, Zou Hua, Zhou Lifang
Occupational Health and Radiation Protection Institute, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, P.R. China.
School of Public Health, School of Medicine, Zhejiang University, Hangzhou, China.
BMC Public Health. 2025 Apr 12;25(1):1378. doi: 10.1186/s12889-025-22604-8.
Pesticide poisoning has emerged as a significant public health concern on a global scale. China has a diverse range of agricultural practices and varying pesticide usage across its regions. Nevertheless, there is a paucity of research on the epidemiology of pesticide poisoning in China. To address this research gap, our study was undertaken to investigate the epidemiological characteristics of pesticide poisoning in Zhejiang Province.
Pesticide poisoning data for Zhejiang Province from 2008 to 2022 was extracted from the National Occupational Disease and Occupational Health Information Monitoring System. A descriptive statistical analysis had been employed to explore the temporal, demographic, and regional distribution of pesticide poisoning cases. Furthermore, logistic regression models were conducted to analyze the influence factors of pesticide-related death.
Between the years 2008 and 2022, totally 64,605 pesticide poisoning cases were observed in Zhejiang Province, with a case fatality rate of 5.28%. The incidence rate was estimated as 7.23 per 100,000 population. The poisoning cases number, incidence rates and the case fatality rates all exhibited fluctuating decreasing trends during the study period. Intentional poisoning (suicide) accounted for 64.64% of all poisoning cases, and the case fatality rate of intentional poisoning cases were also significantly higher than occupational and accidental poisoning. In examining the influence factors of pesticide-related death, it was revealed that older individuals, males, and those experiencing either accidental or intentional poisoning had higher risk of death. The analysis also identified that patients treated in township level hospitals exhibited a higher risk of death compared with those in district/county level or provincial/municipal level primary care hospitals.
The current situation of pesticide poisoning in Zhejiang Province remains severe and the government should further strengthen the monitoring and governing of pesticide. Moreover, it is imperative that mental health education and early psycho-social interventions be given greater emphasis to effectively reduce pesticide-related suicides.
农药中毒已成为全球范围内重大的公共卫生问题。中国农业生产方式多样，各地区农药使用情况各异。然而，中国关于农药中毒流行病学的研究匮乏。为填补这一研究空白，我们开展了本研究以调查浙江省农药中毒的流行病学特征。
从国家职业病与职业健康信息监测系统中提取了浙江省2008年至2022年的农药中毒数据。采用描述性统计分析来探究农药中毒病例的时间、人口统计学和地区分布。此外，进行逻辑回归模型分析农药相关死亡的影响因素。
2008年至2022年期间，浙江省共观察到64,605例农药中毒病例，病死率为5.28%。发病率估计为每10万人7.23例。在研究期间，中毒病例数、发病率和病死率均呈现波动下降趋势。故意中毒（自杀）占所有中毒病例的64.64%，故意中毒病例的病死率也显著高于职业中毒和意外中毒。在研究农药相关死亡的影响因素时发现，老年人、男性以及意外或故意中毒者死亡风险更高。分析还发现，与在区/县级或省/市级基层医院治疗的患者相比，在乡镇级医院治疗的患者死亡风险更高。
浙江省农药中毒现状依然严峻，政府应进一步加强对农药的监测和管理。此外，必须更加重视心理健康教育和早期心理社会干预，以有效减少与农药相关的自杀行为。
