• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

细菌代谢体：结构与生物工程的新见解。

Bacterial metabolosomes: new insights into their structure and bioengineering.

机构信息

Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, L69 7ZB, UK.

College of Marine Life Sciences, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Ocean University of China, Qingdao, 266003, China.

出版信息

Microb Biotechnol. 2021 Jan;14(1):88-93. doi: 10.1111/1751-7915.13740. Epub 2021 Jan 6.

DOI:10.1111/1751-7915.13740
PMID:33404191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7888463/
Abstract

Bacterial metabolosomes have been discovered for over 25 years. They play essential roles in bacterial metabolism and pathogenesis. In this crystal ball paper, I will discuss the recent advances in the fundamental understanding and synthetic engineering of bacterial metabolosomes.

摘要

细菌代谢体已经被发现超过 25 年了。它们在细菌代谢和发病机制中发挥着重要作用。在这篇水晶球论文中，我将讨论在细菌代谢体的基础理解和合成工程方面的最新进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/245d/7888463/d441dfe4aca0/MBT2-14-88-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/245d/7888463/d441dfe4aca0/MBT2-14-88-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/245d/7888463/d441dfe4aca0/MBT2-14-88-g001.jpg

相似文献

1
Bacterial metabolosomes: new insights into their structure and bioengineering.细菌代谢体：结构与生物工程的新见解。
Microb Biotechnol. 2021 Jan;14(1):88-93. doi: 10.1111/1751-7915.13740. Epub 2021 Jan 6.
2
Bio-engineering of bacterial microcompartments: a mini review.细菌微室的生物工程： 一个小型综述。
Biochem Soc Trans. 2019 Jun 28;47(3):765-777. doi: 10.1042/BST20170564. Epub 2019 Jun 24.
3
Eut bacterial microcompartments: insights into their function, structure, and bioengineering applications.真细菌微区室：对其功能、结构及生物工程应用的见解
J Mol Microbiol Biotechnol. 2013;23(4-5):308-20. doi: 10.1159/000351343. Epub 2013 Aug 5.
4
Engineering bacterial translation initiation - Do we have all the tools we need?工程细菌翻译起始 - 我们是否拥有所有需要的工具？
Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt B):3060-3069. doi: 10.1016/j.bbagen.2017.03.008. Epub 2017 Mar 14.
5
The dawning of a 'Golden era' in lantibiotic bioengineering.抗菌肽生物工程的“黄金时代”正在到来。
Mol Microbiol. 2010 Dec;78(5):1077-87. doi: 10.1111/j.1365-2958.2010.07406.x. Epub 2010 Oct 12.
6
Bacterial microcompartments and the modular construction of microbial metabolism.细菌微室和微生物代谢的模块化构建。
Trends Microbiol. 2015 Jan;23(1):22-34. doi: 10.1016/j.tim.2014.10.003. Epub 2014 Nov 14.
7
Withdrawal.撤药；停药；戒除；退出
Environ Microbiol Rep. 2022 Dec 5. doi: 10.1111/1758-2229.12920.
8
Perspective on Biotransformation and De Novo Biosynthesis of Licorice Constituents.甘草成分的生物转化与从头生物合成研究展望
J Agric Food Chem. 2017 Dec 27;65(51):11147-11156. doi: 10.1021/acs.jafc.7b04470. Epub 2017 Dec 13.
9
Morphology engineering of bacteria for bio-production.细菌的生物生产形态工程。
Biotechnol Adv. 2016 Jul-Aug;34(4):435-440. doi: 10.1016/j.biotechadv.2015.12.007. Epub 2015 Dec 19.
10
Bacterial microcompartments insights into the structure, mechanism, and engineering applications.细菌微室：结构、机制与工程应用的深入了解。
Prog Mol Biol Transl Sci. 2011;103:1-20. doi: 10.1016/B978-0-12-415906-8.00008-X.

引用本文的文献

1
Rubisco packaging and stoichiometric composition of the native β-carboxysome in Synechococcus elongatus PCC7942.聚球藻PCC7942中天然β-羧酶体的核酮糖-1,5-二磷酸羧化酶/加氧酶包装及化学计量组成
Plant Physiol. 2024 Dec 24;197(1). doi: 10.1093/plphys/kiae665.
2
Molecular principles of the assembly and construction of a carboxysome shell.羧化体外壳的组装和构建的分子原理。
Sci Adv. 2024 Nov 29;10(48):eadr4227. doi: 10.1126/sciadv.adr4227.
3
Rubisco packaging and stoichiometric composition of a native β-carboxysome.天然β-羧基体的核酮糖-1,5-二磷酸羧化酶/加氧酶包装及化学计量组成

本文引用的文献

1
Reprogramming bacterial protein organelles as a nanoreactor for hydrogen production.将细菌蛋白细胞器重新编程为生产氢气的纳米反应器。
Nat Commun. 2020 Oct 28;11(1):5448. doi: 10.1038/s41467-020-19280-0.
2
Molecular simulations unravel the molecular principles that mediate selective permeability of carboxysome shell protein.分子模拟揭示了介导羧化体外壳蛋白选择性通透性的分子原理。
Sci Rep. 2020 Oct 15;10(1):17501. doi: 10.1038/s41598-020-74536-5.
3
Membrane Dynamics in Phototrophic Bacteria.光合细菌中的膜动态
bioRxiv. 2024 Sep 21:2024.09.20.614183. doi: 10.1101/2024.09.20.614183.
4
Nanoengineering Carboxysome Shells for Protein Cages with Programmable Cargo Targeting.用于具有可编程货物靶向功能的蛋白质笼的纳米工程化羧基体外壳
ACS Nano. 2024 Mar 12;18(10):7473-7484. doi: 10.1021/acsnano.3c11559. Epub 2024 Feb 7.
5
Intrinsically disordered CsoS2 acts as a general molecular thread for α-carboxysome shell assembly.无规则卷曲的 CsoS2 作为α-羧化体外壳组装的通用分子线。
Nat Commun. 2023 Sep 7;14(1):5512. doi: 10.1038/s41467-023-41211-y.
6
Single-particle cryo-EM analysis of the shell architecture and internal organization of an intact α-carboxysome.单颗粒冷冻电镜分析完整的α-羧基体的壳结构和内部组织。
Structure. 2023 Jun 1;31(6):677-688.e4. doi: 10.1016/j.str.2023.03.008. Epub 2023 Apr 3.
7
Kinetic compartmentalization by unnatural reaction for itaconate production.通过非自然反应进行动力学隔室化以生产衣康酸。
Nat Commun. 2022 Sep 12;13(1):5353. doi: 10.1038/s41467-022-33033-1.
8
Probing the Internal pH and Permeability of a Carboxysome Shell.探究羧酶体壳的内部 pH 值和通透性。
Biomacromolecules. 2022 Oct 10;23(10):4339-4348. doi: 10.1021/acs.biomac.2c00781. Epub 2022 Sep 2.
9
Structure and assembly of cargo Rubisco in two native α-carboxysomes.两种天然 α-羧化酶体中货物 Rubisco 的结构和组装。
Nat Commun. 2022 Jul 25;13(1):4299. doi: 10.1038/s41467-022-32004-w.
10
Biogenesis of a bacterial metabolosome for propanediol utilization.细菌代谢体用于 1,2-丙二醇利用的生物发生。
Nat Commun. 2022 May 25;13(1):2920. doi: 10.1038/s41467-022-30608-w.
Annu Rev Microbiol. 2020 Sep 8;74:633-654. doi: 10.1146/annurev-micro-020518-120134. Epub 2020 Jul 20.
4
Structural variability, coordination and adaptation of a native photosynthetic machinery.天然光合作用机器的结构变异性、协调性和适应性。
Nat Plants. 2020 Jul;6(7):869-882. doi: 10.1038/s41477-020-0694-3. Epub 2020 Jul 13.
5
Rubisco accumulation factor 1 (Raf1) plays essential roles in mediating Rubisco assembly and carboxysome biogenesis.核酮糖-1,5-二磷酸羧化酶/加氧酶积累因子1（Raf1）在介导核酮糖-1,5-二磷酸羧化酶/加氧酶组装和羧酶体生物发生中起关键作用。
Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):17418-17428. doi: 10.1073/pnas.2007990117. Epub 2020 Jul 7.
6
Decoding the stoichiometric composition and organisation of bacterial metabolosomes.解析细菌代谢体的化学计量组成和结构。
Nat Commun. 2020 Apr 24;11(1):1976. doi: 10.1038/s41467-020-15888-4.
7
Effect of metabolosome encapsulation peptides on enzyme activity, coaggregation, incorporation, and bacterial microcompartment formation.代谢体包封肽对酶活性、共聚集、掺入和细菌微隔间形成的影响。
Microbiologyopen. 2020 May;9(5):e1010. doi: 10.1002/mbo3.1010. Epub 2020 Feb 13.
8
Encapsulation mechanisms and structural studies of GRM2 bacterial microcompartment particles.GRM2 细菌微隔间颗粒的包封机制和结构研究。
Nat Commun. 2020 Jan 20;11(1):388. doi: 10.1038/s41467-019-14205-y.
9
Comparative Genomic Analysis Reveals Novel Microcompartment-Associated Metabolic Pathways in the Human Gut Microbiome.比较基因组分析揭示了人类肠道微生物群中与新型微区室相关的代谢途径。
Front Genet. 2019 Jul 4;10:636. doi: 10.3389/fgene.2019.00636. eCollection 2019.
10
Single-Organelle Quantification Reveals Stoichiometric and Structural Variability of Carboxysomes Dependent on the Environment.单细胞器定量分析揭示了依赖于环境的羧基体的化学计量和结构变异性。
Plant Cell. 2019 Jul;31(7):1648-1664. doi: 10.1105/tpc.18.00787. Epub 2019 May 2.